38例高龄铜绿假单胞菌肺部感染的临床分析  

Analysis of 38 elderly patients with pseudomonas aeruginosa lung infection

作　　者：吴宁[1] 钱晓明[1] 刘玉亭[1] 

机构地区：[1]南京军区南京总医院老年三科,江苏南京210002

出　　处：《中华保健医学杂志》2009年第3期202-204,共3页Chinese Journal of Health Care and Medicine

基　　金：南京市科技计划基金资助项目(2007020661)

摘　　要：目的探讨铜绿假单胞菌肺部感染的现状及对策。方法回顾性分析本院2006年5月～2008年5月发生的38例高龄铜绿假单胞菌肺部感染的临床资料。结果在本组高龄铜绿假单胞菌肺部感染中院内获得性肺炎占92.1%(35/38),抗生素药敏试验表明细菌耐药率高。死亡率达34.2%(13/38)。易感因素有:高龄、免疫功能低下、住院时间长、机械通气、患有慢性阻塞性肺疾病、长期大量的经验性使用广谱抗生素。结论铜绿假单胞菌肺部感染是医院获得性肺炎最常见的一种,多发生在有多种基础疾病的高龄患者,细菌耐药发生率高,病死率高。尽早做病原学检查,合理应用抗生素,免疫营养支持十分重要。Objective Research on pseudomonas aeruginosa lung infection. Methods The clinical data of 38 elderly patients with pseudomonas aeruginosa lung infection in recent two years were analyzed. Results 92.1% of this group of elderly patients with pseudomonas aeruginosa lung infection was showed that drug resistance of bacterial was high. The mortality hospital acquired pneumonia（35/38）. Antibiotic sensitivity test rate was 34.2%（13/38）. Predisposing factors included old age, low immune function, long hospitalization time, mechanical ventilation, chronic obstructive pulmonary disease （COPD）and overuse of broad-spectrum antibiotics. Conclusions Pseudomonas aeruginosa lung infection is one of the most common hospital acquired pneumonia, and often occur to elderly patients with basic diseases. The incidence of drug resistance and mortality rate are high. Hence ,early pathogenic examination, properly using antibiotics and immune-enhancing diets are very important.

关 键 词：肺部感染 铜绿假单胞菌 易感因素 耐药 

分 类 号：R563.1[医药卫生—呼吸系统]