间氨基苯酚修饰玻碳电极测定多巴胺  

Determination of Dopamine at m-Aminophenol Modified Glassy Carbon Electrode

作　　者：唐明宇[1] 袁若[1] 柴雅琴[1] 欧朝凤[1] 谢轶[1] 高凤仙[1] 

机构地区：[1]西南大学化学化工学院重庆市现代分析化学重点实验室,重庆400715

出　　处：《理化检验（化学分册）》2009年第6期701-703,706,共4页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

基　　金：国家自然科学基金(20675064);重庆市自然科学基金(CSTC-2004BB4149;2005BB4100);西南大学高新技术培养基金(XSGX02)

摘　　要：玻碳电极在含有2．0mmol·L^-1间氨基苯酚的0．1mol·L^-1的三水合高氯酸锂溶液中，于0～1．5V的电位范围内进行电化学修饰，制备了间氨基苯酚修饰电极（m-AP／GCE）。研究发现：间氨基苯酚修饰电极对多巴胺有良好的电催化作用，多巴胺在该电极上出现了一对氧化还原峰，相对于裸玻碳电极，氧化还原峰电位差为减至70mV，提出了用循环伏安法测定多巴胺的方法。氧化峰电流与多巴胺的浓度在1．2×10^-7～9．1×10^-6和9．1×10^-6～1．2×10^-8mol·L^-1范围内呈线性关系，检出限（3S／N）为3．2×10^-8mol·L^-1。The glassy carbon electrode （GCE） was modified electrochemically on its surface with m- aminophenol （m-AP） in 0. 1mol·L^-1 LiClO4 solution containing 2. 0 mmol · L^-1 m-AP at the potential of 0-1.5 V. This modified electrode described above was named abbreviately as m-AP/GCE. It was found that significant catalytic action of the m-AP/GCE was observed on the reaction of dopamine （DA） at the electrode. DA showed a pair of oxidation peak and reduction peak at m-AP/GCE, with potential difference of oxidation peak and reduction peak reduced to a value of 70mV as compared with its reaction at the bare GCE, Based on these findings, a selective method for determination of DA by cyclic voltammetry was proposed. Linear relationships between values of oxidation peak current and concentration of DA were obtained in the ranges of 1.2×10^-7～9.1×10^-6 and 9.1×10^-6～1.2×10^-8mol·L^-1, with detection limit （3S/N） of 3. 2×10^-8mol·L^-1.

关 键 词：间氨基苯酚 多巴胺 化学修饰电极 电催化 

分 类 号：O657.1[理学—分析化学]