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机构地区:[1]华中科技大学同济医学院附属同济医院泌尿外科,湖北武汉430030
出 处:《中华男科学杂志》2009年第6期526-529,共4页National Journal of Andrology
摘 要:目的:探讨以扩大的阴股沟皮瓣一期再造阴茎的可行性,提高再造阴茎成活率,缩短阴茎再造周期,从而改良阴股沟皮瓣阴茎再造方法,为临床应用提供实验基础。方法:健康成年雄性新西兰大白兔36只,随机均分成实验组(扩大阴股沟皮瓣组,EPTF组)和对照组(阴股沟皮瓣组,PTF组)。实验组以兔一侧扩大的阴股沟皮瓣(阴股沟皮瓣+阴部外浅动脉股皮支皮瓣)一期再造阴茎体,对侧阴部外浅动脉股皮支皮瓣再造尿道。对照组以兔双侧阴股沟皮瓣一期再造阴茎体和尿道。结果:实验组再造阴茎成活率为83.33%(15/18),漏尿率为55.56%(10/18);对照组成活率为38.89%(7/18),漏尿率为72.22%(13/18);再造阴茎成活率实验组显著高于对照组(P<0.05),而漏尿率两组无显著性差异。结论:扩大的阴股沟皮瓣一期阴茎再造成活率高,可替代阴股沟皮瓣阴茎再造。Objective: To investigate the feasibility of one-stage phallic reconstruction with the extended pudendal-thigh flap (EPTF) to achieve a higher survival rate, shorter surgical cycle, and more experimental evidence for the clinical application of the technique. Methods: We equally randomized 36 healthy adult New Zealand rabbits to an experimental and a control group to receive one-stage phallic reconstruction, the former with EPTF ( pudendal-thigh flap + thigh cutaneous branches of the superficial external pudendal artery, PTF + TCB), the urethra reconstructed with the TCB flap, and the latter with bilateral pudendal-thigh flaps. Results: The survival rate of the reconstructed phallus was 83.33% (15 / 18) and the urine leakage was 55.56% (10/18 ) in the experimental group, as compared with 38.89 % ( 7/18 ) and 72.22 % ( 13 / 18 ) in the controls. Conclusion : One-stage phallic reconstruction with EPTF, with its higher survival rate and shorter surgical cycle, is a desirable substitute for phallic reconstruction with bilateral pudendal-thigh flaps.
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