胶原酶溶解术治疗腰椎间盘突出症疗效分析  

The Analysis of Therapeutic Effect in Treating Lumbar Intervertebral Disc Herniation with Collagenase Chemolysis

作　　者：张洪新[1] 陈岚[1] 王珩[1] 王执民[1] 吴智群[1] 郭卫平[1] 曹炜[1] 宫卫东[1] 倪代会[1] 李文献[1] 

机构地区：[1]第四军医大学唐都医院介入放射科,陕西西安710038

出　　处：《实用放射学杂志》2009年第6期866-868,878,共4页Journal of Practical Radiology

摘　　要：目的评价胶原酶溶解术的近、中、远期疗效。方法对1279例行胶原酶溶解术、资料完整的腰椎间盘突出症患者进行随访观察，随访时间和例数分别为：0．5～1年（近期）1011例，2～4年（中期）967例，6～8年（远期）661例，按统一的疗效标准评价胶原酶溶解术的近、中、远期疗效。结果最佳适应证近期、中期、远期优良率分别为89．5％、82．4％、80．4％。结论在最佳适应证范围内，胶原酶溶解术是腰椎间盘突出症的一种有效的微创治疗方法。Objective To evaluate the early,medium--term and long--term therapeutic effect of collagenase chemolysis for lumbar intervertebral disc herniation. Methods 1279 patients with lumbar intervertebral disc herniation who had integral data and received collagenasechemolysis were followed. Following time and number of cases were：0.5~1 year（early） and 1011 cases,2~4 years （medium--term） and 967 cases, 6~ 8 years（long--term） and 661 cases. The early, medium--term and long--term therapeutic effects of collagenase chemolysis were evaluated with uniform therapeutic effect criterion. Results The effective rate of the early,me- dium-term and long--term were 89.5% ,82.4% and 80.4%respectively in treating lumbar disc herniation if to be the best of indication. Conclusion The collagenase chemolysis is a effective and mini--invasive treatment for lumbar intervertebral disc herniation when which is the best of indication.

关 键 词：脊椎 胶原酶 腰椎间盘突出症 疗效 

分 类 号：R681.53[医药卫生—骨科学] R815[医药卫生—外科学]