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作 者:徐浣白[1] 张晓梅[1] 潘明麟[1] 黄詠齐[1] 石建华[1] 时照明[1] 陈凤玲[1] 周纯先[1] 孙卫华[1] 张士荣[1] 陈建文[1]
机构地区:[1]蚌埠医学院第一附属医院内分泌科
出 处:《实用医学杂志》2009年第12期1960-1962,共3页The Journal of Practical Medicine
基 金:安徽省卫生厅基金资助项目(编号:2002A040)
摘 要:目的:1995年在蚌埠地区开展了第2次糖尿病(diabetes mellitus,DM)流行病学普查,10年间,扩大DM三级防治网,提高防治水平。方法:指导1995年2282人中普查出的60例T2DM者予生活方式及药物干预,10年间对各项临床指标进行随访调查。结果:60例T2DM患者先后服用降糖药治疗者>37.3%;病情重或慢性并发症多者,应用胰岛素替代疗法或与口服降糖药联用或先后阶段性应用,约占56.9%;病情较轻仅以饮食和体育锻炼治疗者占5.9%。血糖、血压控制较理想,血脂、尿白蛋白排泄率需加强控制。并发症中急性者少,慢性并发症增多。10年病死率为10.5%(6/57),主要死亡因素依次为心脑血管病、慢性肾功能不全、多脏器功能衰竭、恶性肿瘤等。结论:DM可防可治,应做到尽早发现、综合强化治疗,进一步加强DM三级预防工作。Objective To expand the three grades network and improve the levels of prevention and treatment of type 2 diabetes mellitus, the second epidemiological survey of diabetes mellitus in Bengbu region was conducted from 1995 to 2005. Methods Clinical parameters in 60 cases with type 2 diabetes mellitus found from 2 282 subjects in the survey who received intervention of life style and drugs were detected during the 10 years. Results Over 37.3% cases received oral hypoglycemie agents, almost 56.9% cases with serious state or multiple chronic complications received insulin substitution therapy alone, or combined with oral hypoglycemic agents, or stage application in succession. 5.9% cases with gentle state received diet and physical exercise. The blood glucose and blood pressure were under control, but blood fat and urinary albumin excretion rate needed to receive enhanced control. Incidence of chronic complications was increased. The mortality rate was 10.5% during the 10 years, and the major causes of death were cardiovascular and cerebrovascular diseases, chronic renal dysfunction, chronic muhiorgan dysfunction, and malignant tumour. Conclusion Type 2 diabetes mellitus is preventable and treatable, and should be found as early as possible and receive general intervention. The three grades of prevention against Type 2 diabetes mellitus should be strengthened.
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