关于粒细胞集落刺激因子来源的探讨  

Studies of the origin of granulocyte colony stimulate factor(GCSF)

作　　者：刘桂兰[1] 魏艳秋[1] 蒋佩华 田开功 孙敏[1] 杨铁生[1] 樊春红[1] 

机构地区：[1]北京医科大学人民医院儿科

出　　处：《北京医学》1998年第3期143-145,共3页Beijing Medical Journal

摘　　要：应用Ｇ－ＣＳＦＥＬＩＳＡ试剂盒，分别测定了４８例怀孕３７～３８周健康孕妇静脉血清，５０例正常足月儿脐静脉血清和４９例脐动脉血清Ｇ－ＣＳＦ阳性率和含量。结果他们的阳性率分别为８．３３％，７４％和８．１６％，并测定了３７例阳性脐静脉血中Ｇ－ＣＳＦ的含量，结果Ｓ／Ｎ均值为５．９０±３．９５，经统计学处理，脐静脉血和孕妇静脉血阳性率有显著性差异（Ｐ＜０．０１），脐静脉血与脐动脉血阳性率也有显著性差异（Ｐ＜０．０１）。The GCSF ELISA test boxes were applied to detect the GCSF positive rates and contents in vein serum of forty-eight healthy women with pregnancy from thirty-seven to thirty-eight weeks, inumbilical vein serums of fifty normal appropriate for gestational age infants and in umbilical artery serums of forty-nine normal appropriate for gestational age infants. The results showed that their positive rates were 8.33%,74%,8.16% respectively. We also detected the contents of the GCSF in thirty-seven positive umbilical vein serums. The results showed that the S/N was 5.90±3.95. From statistic analysis, we found that the differences in the positive rates between umbilical vein serums and pregnant women's vein serums were significant (P<0.01),and the differences in positive rates between umbilical vein serums and umbilical artery serums were much large(P<0.01).

关 键 词：孕妇 脐血 粒细胞 集落刺激因子 G-CSF 

分 类 号：R457[医药卫生—治疗学]