结核-聚合酶链反应在诊断结核性胸腔积液中的价值  

The value of TB-PCR in the diagnosis of tuberculous pleural enffusion

作　　者：覃铁和[1] 鲁小燕[1] 王首红[1] 黄思贤[1] 彭锦泉[1] 

机构地区：[1]广东省人民医院呼吸内科

出　　处：《新医学》1998年第7期349-350,共2页Journal of New Medicine

摘　　要：目的：阐明结核－聚合酶链反应（ＴＢ－ＰＣＲ）在诊断结核性胸腔积液中的作用。方法：以胸膜活检病理结果为标准，总结了１１８例胸腔积液ＴＢ－ＰＣＲ的检测结果，并与结核菌涂片、培养两种方法进行了对比。结果：ＴＢ－ＰＣＲ、涂片、培养三种方法的阳性率分别为３３％，０和５％，前者高于后两者（Ｐ＜０．００１）。但ＴＢ－ＰＣＲ的假阴性率较高（６７％）。结论：用ＴＢ－ＰＣＲ法诊断结核性胸腔积液的价值有限。Objective: To elucidate the value of tuberculosis polymerase chain reaction (TBPCR)in the diagnosis of tuberculous pleural effusion. Methods:TBPCR was parformed in 118 patients with pathologic diagnosis of tuberculosis (TB), and compared with pleural fluid smear and culture. Results: The positive rate of the three methods was 33%,0,and 5% respectively. The positive rate of TBPCR was higher than that of smear and culture (P<0001) .But the false negative rate of TBPCR was higher (67%). Conclusion: The value of TBPCR in the diagnosis of tuberculous pleural effusion was limited. Pleural biopsy is the first choice.

关 键 词：结核性 胸腔积液 聚合酶链反应 

分 类 号：R521.704[医药卫生—内科学] R561.04[医药卫生—临床医学]