经静脉心肌声学造影辅助背向散射技术对正常及缺血心肌组织定征的实验研究  

Normal and Ischemic Myocardial Ultrasonic Tissue Characterization: Integrated Backscatter Imaging by the Help of Myocardial Contrast Echocardiography

作　　者：李澎[1] 谢峰[1] 勒斌[1] 刘汉英[1] 刘延玲[1] 

机构地区：[1]北京市中国医学科学院阜外心血管病医院中国协和医科大学心血管病研究所

出　　处：《中国超声医学杂志》1998年第7期6-9,共4页Chinese Journal of Ultrasound in Medicine

基　　金：国家自然科学基金;人事部留学回国人员经费资助

摘　　要：本文探讨背向散射超声成像技术在正常及缺血心肌组织学定征方面的作用。对１０条开胸犬心脏行ＩＢＳ成像，记录并分析结扎冠状动脉左前降支前后其供血范围相应的背向散射周期性变化值（Ｃｙｃｌｉｃｖａｒｉａｔｉｏｎｏｆｉｎｔｅｇｒａｔｅｄｂａｃｋｓｃａｔｅｒ，ＣＶＩＢＳ）变化，并与左回旋支供血区对照。经静脉注射声学造影剂ＦＸ５３０协助评价心肌血流灌注，确定缺血部位。正常前壁心肌ＣＶＩＢＳ为６．６９±０．７２ｄＢ，侧壁为６．５４±０．６３ｄＢ；缺血后心肌ＣＶＩＢＳ前壁３．１８±０．４１ｄＢ，侧壁６．５９±０．５２ｄＢ，ｐ＜０．００１；The objective of this study is to prove the effect of Integrated Ultrasound Backscatter(IBS)in normal and ischemic myocardial tissue characterization by the help of myocardial contrast echocardiography(MCE).We studied 10 open chest dogs(15 21kg).Cyclic variation of integrated backscatter(CVIBS)was measured in the territory of left anterior descending coronary artery(LAD)and the territory of left circumflex branch(LCX) from a two dimensional ultrasound image with an acoustic densitometry software package pre and post holding up of the LAD.MCE helped to assess myocardial perfusion and to provide the evidence of normal and ischemic myocardium.CVIBS was similar in LAD(6 69±0 72dB)and LCX(6 54±0 63dB).CVIBS in LAD area(3 18±0 41dB)was significantly lower than normal but also in LCX area after LAD occlusion(P<0 001).Conclusion:That patterns of CVIBS are different in normal and ischemic myocardium is naturally reasonable.

关 键 词：背向散射 组织定征 心肌声学造影 心肌缺血 

分 类 号：R542.204[医药卫生—心血管疾病]