静脉与硬膜外泵注舒芬太尼自控镇痛的比较  

Comparison of Patient-controlled Analgesia of Intravenous with Epidural Sufentanil

作　　者：刘志强[1] 

机构地区：[1]郑州市第二人民医院麻醉科,郑州450052

出　　处：《中国现代医生》2009年第18期187-188,共2页China Modern Doctor

摘　　要：目的比较术后静脉和经硬膜外应用舒芬太尼自控镇痛(PCA)的临床效果和安全性。方法96例妇科手术病人随机分为静脉注射舒芬太尼自控镇痛(PCIA)组和经硬膜外舒芬太尼自控镇痛组(PCEA),每组48例。两组(PCA)配方均为舒芬太尼150μg+0.9%氯化钠至100mL,持续给药速度2mL/h,单次PCA剂量1.0mL。锁定时间15min,术后定时进行镇痛镇静评分,24h舒芬太尼用量,患者满意度不良反应的观察比较。结果PCIA组24h用药量低于PCEA组(P<0.05),两组镇静评分低且无显著性差异。患者对术后镇痛总体满意度,良好至优秀均在84.6%以上,不良反应发生率两组间无显著性差异。结论舒芬太尼用于术后镇痛安全有效,但舒芬太尼PCIA镇痛效果明显优于舒芬太尼PCEA,且用药量少。Obiective To compare the efficacy and safety of patient-contrdled analgesia（PCA） of intravenous with epidural sufentanil. Methods Ninety-six patients undergoing ordinary hysterectomy were randomly allocated to patient-controlled intravenous analyesia （PCIA） group（n=48） and patient-controlled epidural analgesia（PCEA） group（n=48）, The PCA solution consists of sufentanil 150mg and NS 97mL,The Background in fusion 2mL/mg,bolus 0.SmL,lockout time 15min.The severity of pain,incidence of nausea and vomiting, total dosage of sufentanil usded in 24h,and patient＇s satisfaition were assessed. Results The total dosage of sufentanil administered, the times of temporarily pressing the PCA key and the postoperative pain scores were significantly lower in the PCIA group than those in the PCEA group,Between two groups,there was no signigicant lower in the overall satisfaction rate of pain relief, sedation and vomiting. Conclusion PCIA with sufentanil is better than PCEA with it for postoperative pain relief.

关 键 词：舒芬太尼 镇痛 静脉内 硬膜外 

分 类 号：R614[医药卫生—麻醉学]