原发性肝癌合并胆管癌栓的预后分析  

Prognostic analysis of primary hepatocellular carcinoma with cancer embolus of biliary tract

作　　者：石洁[1] 程树群[1] 吴孟超[1] 何永超[1] 李楠[1] 郭卫星[1] 薛杰[1] 胡华生[1] 

机构地区：[1]第二军医大学东方肝胆外科医院,上海200438

出　　处：《中华肝胆外科杂志》2009年第6期417-419,共3页Chinese Journal of Hepatobiliary Surgery

基　　金：基金项目：本课题受上海市教育发展基金会晨光项目资助（基金编号2007CG48）

摘　　要：目的通过不同部位胆管癌栓的疗效对比，进一步探讨胆道癌栓的预后及其影响因素。方法随访第二军医大学东方肝胆外科医院2000年1月至2003年12月手术治疗的原发性肝癌伴胆管癌栓病人共50例，按胆管癌栓的部位分为A、B、c、D组共4组。结果A、B、c、D各组的中位生存时间分别为11．6个月、2．1个月，8．0个月和7．6个月。B组较其他各组具有显著统计学意义（P〈0．05）。结论原发性肝癌伴胆管癌栓手术治疗可取得较好的疗效，但是不同部位的胆道癌栓的预后并不一样，以伴胆管左支癌栓的预后为最差。Objective To observe the prognosis of hepatocellular carcinoma （HCC） patients with cancer embolus of biliary tract （CEBT）. Methods The clinical data of 50 HCC patients with CEBT underwent hepatectomy and thrombectomy in our hospital from January 2000 to December 2003 were retrospectively analyzed. All the patients were divided into four groups （A, B, C and D） based on distribution and location of CEBT. Results The O. 5-, 1-, 2-and 3-year survival rates were 51.2%, 31. 7Y0, 19.5% and 12.2%, respectively. The median survival time was 11.6, 2. 1, 8.0 and 7.6 months in group A, B, C and D, respectively. Significant difference was found in the survival time between group B with CEBT located in the left hepatic duct and other groups （P〈0.05）. Conclusion Surgery remainsthe most effective treatment for HCC with CEBT. But the therapeutical effect is not the same for CEBT of different locations. The prognosis is the worst in those patients with CEBT lo- cated in the left hepatic duct.

关 键 词：癌 肝细胞 胆管癌栓 预后 

分 类 号：R686[医药卫生—骨科学]