光滑双脐螺基因组计划研究进展  

Progress of research on genome project of Biomphalaria glabrata

作　　者：刘琴[1] 周晓农[1] 

机构地区：[1]中国疾病预防控制中心寄生虫病预防控制所,上海200025

出　　处：《中国血吸虫病防治杂志》2009年第3期235-237,共3页Chinese Journal of Schistosomiasis Control

基　　金：国家自然科学基金(3059037);博士后基金(20070420422)

摘　　要：本文介绍了光滑双脐螺基因组计划的最新研究进展,包括基因组测序、新基因的发现、基因差异表达以及类纤维素蛋白原研究等方面,为理解螺类生物学、综合鉴定水生螺类发育阶段的基因表达、螺和寄生虫共进化机制及自然选择机制、鉴定灭螺药物靶点提供了理论依据,同时也为湖北钉螺的研究提供了科学参考。This paper introduces the latest development of the genome project of Biomphalaria glabrata including the study of genome sequencing, discovering new genes, differential gene expression and fibrinogen-related protein, etc, which would provide theoretic evidence for understanding snail biology, identifying the gene expression of all the developmental stages, the co-evolutionary dynamics that exists in host-parasite interactions and identifying the drugs targets for molluscacide, as well as provide the scientific reference for the study of Oneomelania hupensis.

关 键 词：光滑双脐螺 基因组计划 差异表达基因 类纤维素蛋白原基因 

分 类 号：R383.24[医药卫生—医学寄生虫学]