3-硝基-4-氯苯氨缩3-甲酰基色酮系列席夫碱的合成及抗菌活性研究  

Study on the Synthesis and Antibacterial Activities of Some Schiff Bases Containing 3-Nitro-4-Chloro-3-Formylchromone

作　　者：周红艳[1] 王辉[1] 黄立波[1] 

机构地区：[1]湖北民族学院化学与环境工程学院,湖北恩施445000

出　　处：《湖北民族学院学报（自然科学版）》2009年第2期154-155,共2页Journal of Hubei Minzu University(Natural Science Edition)

基　　金：湖北省高等学校优秀中青年科技创新团队计划资助项目(T200707)

摘　　要：原料3-硝基-4-氯苯氨与3-甲酰基色酮系列化合物缩合得到相应新型席夫碱类化合物,其结构经IR、1H NMR、MS和元素分析确证.体外抗菌活性结果表明,大多数化合物具有较好的抑菌活性.A series of novel Schiff bases were synthesized using the reaction of 3 -nitro -4 -chloroani- line with 3 -formylchromone, and their structures were confirmed by IR, ^1H NMR, MS and elemental analysis. The antibacterial activity was preliminarily evaluated. The results show that most of the prepared compounds have good antibacterial activities.

关 键 词：3-甲酰基色酮 席夫碱 合成 

分 类 号：O621[理学—有机化学]