研究型综合化学新实验——反式-2,3-二氢呋喃的立体选择性合成及其表征  

A new research-oriented comprehensive chemistry experiment:Stereoselective synthesis of trans-2,3-dihydrofuran and its structural identification

作　　者：张慧[1] 曹卫国[1] 童玮琦[1] 丁益民[1] 包新华[1] 方建慧[1] 

机构地区：[1]上海大学理学院化学系

出　　处：《实验技术与管理》2009年第6期124-128,共5页Experimental Technology and Management

摘　　要：介绍了一个综合化学新实验——反式2噻吩基-α-甲酰基-3（4-硝基苯基）-4-乙酰基-5-甲基-2，3-二氢呋喃的立体选择性合成及其表征。整个实验将立体合成方法与现代仪器分析技术巧妙结合，由红外光谱、质谱、核磁共振氢谱、元素分析等多种仪器分析方法来确定产物的最终结构，由^1H-^1H NOESY和单晶X-射线衍射确定产物构型。The stereoselective synthesis of trans-2-thien-oyl-3 [4 nitrophenyl]-4-acetyl- 5-methyl-2,3-dihydro furan and its structural identification are introduced as a new comprehensive chemistry experiment in detail. The whole experiment combined the method of the stereoselective synthesis with the modern instrumental analysis technology. The structure of the product was confirmed by IR, MS, 1H NMR, ^1H--^1H COSY, 1H --^1H NOESY, microanalysis and single crystal X-ray diffraction analysis. The possible reaction mechanism was confirmed as well.

关 键 词：立体选择性合成 胂叶立德 二氢呋喃 综合化学实验 仪器分析 谱图解析 

分 类 号：G642.0[文化科学—高等教育学]