咪达唑仑对偏头痛发作的预防作用  

The Role of Midazolam in The Prevention of Migraine Attack

作　　者：王丹丹[1] 

机构地区：[1]南京中医药大学附属医院麻醉科,南京210029

出　　处：《中国医药导刊》2009年第6期982-983,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:观察咪达唑仑对偏头痛发作的预防作用。方法:20例符合国际头痛学会诊断标准的患者,随机分为治疗组和对照组,分别服用咪达唑仑7.5mg、安慰剂。记录头痛的发作次数、持续时间和疼痛程度。结果:治疗组发作次数、发作时间治疗前后有显著性差异(P<0.05),治疗组治疗后发作时间与对照组比较有显著性差异(P<0.05)结论:咪达唑仑对偏头痛的发作有一定预防作用。Objective： To observe the preventive effect of midazolam on migraine attack. Methods：Twenty cases who met the International Classification of Headache Disorders（ICHD） diagnostic criteria were randomly divided into treatment group and control group , were used midazolam 7.5mg/d or placebo separately.Recorded the numbers of migraine attacks, duration and degree of pain. Results： The attack frequency, attack time of treatment group before and after treatment were significantly different （P 〈0.05）, the duration of treatment group after treatment compared with the control group were significantly different （P〈0.05）. Conclusions：Midazolam on the migraine attack has a certain preventive effect.

关 键 词：偏头痛 咪达唑仑 预防 

分 类 号：R965[医药卫生—药理学] R747.2[医药卫生—药学]