磁性纳米材料及其在癌症诊疗中的应用  

Magnetic Nanomaterials and Their Applications in Diagnosis and Treatment of Cancer

作　　者：陈庆梅[1,2] 宗小林[2] 

机构地区：[1]江西中医学院计算机系,南昌330006 [2]浙江大学生物医学工程教育部重点实验室,杭州310027

出　　处：《微纳电子技术》2009年第6期340-345,共6页Micronanoelectronic Technology

摘　　要：磁性纳米材料在不同的尺寸下分别呈现出铁磁性和超顺磁性。介绍了不同形式和用途的磁性纳米材料,包括磁性纳米颗粒、磁性脂质体、磁流体、铁磁微晶玻璃、碳铁复合物、超顺磁性氧化铁等,并对近年来磁性纳米材料在磁共振成像、肿瘤细胞分离、肿瘤靶向热疗、栓塞治疗及药物磁导向方面的应用进行了综述。总结了磁性纳米材料在癌症诊断及治疗中的作用和面临的困难,并对磁性纳米材料在深部肿瘤的诊断及癌症的联合治疗、基因治疗等应用方向进行了展望。Magnetic nanomaterials have the ferromagnetism and the superparamagnetism in different dimensions. Different magnetic nanomaterials for different purposes are introduced, such as the magnetic nanogranule, magnetic liposome, magnetic liquid, ferromagnetic minicrystal glass, ironcarbon compound and superparamagnetic ironoxide. Recent applications of magnetic nanomaterials in the magnetic resonance imaging, separation of tumour cells, target hot treatment, embolism treatment and magnetic target of drug are reviewed. In the end, the actions of magnetic nanomaterials on the diagnosis and treatment of cancer are summarized, and their applications in the diagnosis of deep tumours, combined treatment and gene treatment of cancers are prospected.

关 键 词：磁性纳米材料 肿瘤 磁共振成像 靶向热疗 磁导向 

分 类 号：O482.54[一般工业技术—材料科学与工程] O482.52[理学—固体物理]