心理干预治疗急性冠脉综合症合并抑郁症的疗效  

Effects of mental treatment on symptom and mortality in patients with acute coronary syndrome and depression

作　　者：董照辉[1] 隋海燕[1] 杨卫边[1] 

机构地区：[1]宿迁市沭阳县人民医院心内科,江苏宿迁223600

出　　处：《心血管康复医学杂志》2009年第3期222-224,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:研究抗抑郁及心理治疗对急性冠脉综合征(ACS)合并抑郁症患者临床症状(胸闷、心悸、气短、胸痛等)缓解情况及住院期间病死率的影响。方法:住院的ACS合并抑郁症患者60例,随机被分为治疗组30例和对照组30例,对照组给予硝酸酯类、血管紧张素转换酶抑制剂(ACEI)、美托洛尔、辛伐他汀等药物治疗。治疗组在上述治疗方案的基础上加阿米替林(25mg/d)及心理疏导治疗。观察抗抑郁心理治疗对患者住院期间临床症状缓解情况及病死率的影响。结果:治疗组患者临床症状缓解率显著高于对照组(93.3%∶73.3%,P<0.05);住院期间病死率显著低于对照组(3.3%∶23.3%,P<0.05)。结论:对急性冠脉综合征合并抑郁症患者进行抗抑郁及心理疏导治疗,可改善患者的临床症状及降低病死率。Objective： To observe the therapeutic effect of mental treatment on clinical symptom and mortality in patients with acute coronary syndrome （ACS） and depression. Methods： The 60 ACS patients with depression were randomly divided to treatment group （30 patients） and control group （30 patients）. The control group received routine therapy （include ACEI, metoprolol, simvastatin etc. ）. The treatment group received amitriptyline （25 mg/d） and mental treatment above the base of routine therapy. The therapeutic effect on clinical symptom and mortality was observed in two groups. Results： There were significant difference of clinical syndrome catabatic rate between two groups （93.3%： 73.3, X^2=4. 320, P〈0.05） . There were significant difference of mortality between two groups （3.3% ： 23.3%, 2.2 =5. 192, P〈0.05）. Conclusion： The anti-depression and mental treatment may improved clinical symptom and decrease mortality in patients with ACS and depression.

关 键 词：心理疗法 冠状动脉疾病 抑郁症 

分 类 号：R359.109[医药卫生—基础医学]