国内外肝癌射频消融术与手术切除3年生存率Meta分析  

Meta-ANALYSIS OF DOMESTIC AND OVERSEASES THREE-YEAR SURVIVAL IN PATIENTS WITH LIVER CANCER TREATED WITH RADIOFREQUENCY ABLATION VERSUS HEPATECTOMY

作　　者：师礼鹏[1] 王一[2] 

机构地区：[1]青岛大学医学院附属青岛市市立医院东院肝胆外科,山东青岛266071 [2]青岛市市立医院肝胆外科

出　　处：《齐鲁医学杂志》2009年第5期413-415,共3页Medical Journal of Qilu

基　　金：青岛市卫生局医药学科科研项目(2004-wsxk003)

摘　　要：目的比较肝癌射频消融术与手术切除治疗的临床效果。方法通过计算机检索和手工检索全面收集关于射频消融术与手术切除治疗肝癌的临床对照研究文献,并按Cochrane协作网推荐的方法进行Meta分析。采用固定效应模型,对符合纳入标准的6个实验共736例病人进行Meta分析。结果与手术组相比,射频消融组的术后3年生存率低,差异有显著性[RR=1.25,95%CI=(1.00,1.57),P<0.05]。结论应用射频消融术治疗肝癌3年后病人死亡的相对危险度是手术切除的1.25倍,手术切除术治疗肝癌疗效优于射频消融术。Objective To compare the therapeutic effects of radiofrequency ablation versus hepetectomy for liver cancer. Methods Clinical data of patients with liver cancer underwent radiofrequency ablation or hepatectomy were collected from literature via electronic searching and handwork-searching. Meta-analysis that recommended by Cochrane Collaboration was done for the data obtained, 736 patients who met the six criteria of enrollment were included in this study using fixed-effect model. Results Compared with that of surgery, three year survival in those underwent radiofrequency ablation was statistically lower [RR 1.25, 95 % CI= （1.00,1.57）,P〈0.05]. Conclusion Applying radiofrequency ablation, the relative risk of death after three years of therapy is higher than surgical resection. The therapeutic outcome of surgery is better than the ablation.

关 键 词：肝肿瘤 导管消融术 外科手术 META分析 

分 类 号：R657.3[医药卫生—外科学]