Q-T间期延长综合征患者的全身麻醉  

General anesthesia for patients with long Q-T syndrome

作　　者：王家和[1] 王惠军[1] 成文聪[1] 

机构地区：[1]首都医科大学附属北京同仁医院麻醉科,100730

出　　处：《临床麻醉学杂志》2009年第6期490-492,共3页Journal of Clinical Anesthesiology

摘　　要：目的总结Q-T间期延长综合征(LQTS)患者全身麻醉的经验。方法LQTS患者36例,采用咪唑安定0.1mg/kg、依托咪酯0.3mg/kg、芬太尼5μg/kg、维库溴铵0.1mg/kg麻醉诱导,插管后吸入60%N2O和1%～2%异氟醚,并间断追加芬太尼和维库溴铵维持麻醉。持续监测BP、HR、SpO2和PETCO2。记录麻醉前和术中ECG,测量Q-T值并计算出Q-Tc值。术后应用芬太尼、咪唑安定静脉镇痛镇静。结果所有患者各时点BP、HR差异无统计学意义。与麻醉前相比,个别患者麻醉诱导后Q-Tc值有轻微下降,但Q-T间期无明显延长;术中无心律失常等心血管意外发生。结论此种麻醉方式及用药对LQTS患者是安全有效的。Objective To summerize the experience of general anesthesia in 36 patients with long Q-T syndrome （LQTS）. Methods The anesthesia in all LQTS patients was induced with midazolam 0. 1 mg/kg, etomidate 0. 3 mg/kg, fentanyl 5 μg/kg and vecuronium 0. 1 mg/kg, and maintained by inhaling 60% N2O and 1%- 2% isoflurane. BP, HR, SpO2 and PET CO2 were monitored. ECG at the different time points was record. The Q-T intervals were measured and the Q-Tc was calculated. Results BP and HR were not significantly changed during operation in all cases. The Q-T intervals were not prolonged during operation with a little decline of Q-Tc. There was no any case with arrhythmia or other vascular events. Conclusion The anesthesia regime used in this group of LQTS patients is effective and safe.

关 键 词：Q-T间期 Q-T间期延长综合征 麻醉 

分 类 号：R614[医药卫生—麻醉学]