植人式微型轴流血泵的研制及体外实验研究  

Development and in vitro study of miniature implantable axial flow blood pump

作　　者：王玉璇[1] 张杰民[1] 施超[1] 刘晓程[1] 

机构地区：[1]北京协和医学院,中国医学科学院,泰达国际心血管病医院辅助循环研究室,天津300457

出　　处：《中国医师杂志》2009年第6期730-733,共4页Journal of Chinese Physician

基　　金：2009年天津市科技支撑计划重点项目

摘　　要：目的近年来，叶轮血泵的研究已经成为心脏外科和生物医学工程领域关注的焦点。通过体外模拟循环实验台对自行研发设计的微型轴流血泵进行测试，探讨血泵的体外流体力学特性。方法分别利用水及30％甘油水溶液作为循环介质模拟血液在体外模拟循环条件下进行血泵流体力学测试。结果在血泵转速为13000rpm，压力为100mmHg时，分别以水及30％甘油水溶液作为循环介质，其对应流量达到6．19L／min和5．08L／min。结论该轴流血泵的基本流体力学性能良好，其流体力学特性已经完全可以替代左心室功能，满足临床心衰患者辅助循环需求。Objective The research of impeller blood pump has been the key point in cardiac surgery and biomedical engineering fields in recent years. To investigate hydrodynamics of self researched and developed mini axial flow pump, parameters of pump were tested on a homemade mimic vitro platform. Methods Hydrodynamics tests were performed in vitro mimic circulation, water and 30% glycerin in water as respective circulatory mediator to simulate blood. Results Flow rates can reach 6. 19L/min and 5.08L/min respectively in water and 30% glycerin, when rotation speed was 13000rpm and pressure was 100mmHg. Conclusion Axial flow blood pump has good hydrodynamics to substitute for left ventricle, which can meet the demand of assisted circulation in congestive heart failure patients.

关 键 词：输血 仪器和设备 心脏辅助装置 临床研究 

分 类 号：TH7[机械工程—仪器科学与技术]