不同剂量美沙酮维持治疗患者渴求感与生存质量研究  

Study of Craving and Quality of Life for the Drug Abusers Accepting Different Dosages of Methadone

作　　者：李杏莉[1] 谭红专[1] 孙振球[1] 张恒[1] 陈梦施[1] 欧秋英[2] 

机构地区：[1]中南大学公共卫生学院,湖南长沙410078 [2]湖南省疾病预防控制中心,湖南长沙410005

出　　处：《中国临床心理学杂志》2009年第3期365-366,共2页Chinese Journal of Clinical Psychology

基　　金：第四轮中国全球基金/中英艾滋病项目应用研究(2008OR47)

摘　　要：目的:探讨接受不同剂量水平的美沙酮维持治疗的海洛因成瘾者的"渴求"程度、"生存质量"改善及两者的关系。方法:采用生存质量简表(WHO-QOLBRIEF)、海洛因渴求问卷分别在患者入组治疗时、治疗后6个月随访调查。结果:①接受美沙酮治疗后患者的"渴求"程度降低、服用高剂量美沙酮的患者"渴求"程度改善更为明显;②接受美沙酮治疗后患者生存质量有所改善,但不同剂量组患者"生存质量"改善无差异;③"渴求"和"生存质量"具有负相关关系,而且在治疗前后保持相对稳定,相关系数分别为r1=-0.451;r2=-0.450。结论:高剂量的美沙酮有助于减少患者对"海洛因"等毒品的渴求。渴求感与生存质量存在负相关关系。Objective： To explore the change of craving and quality of life and the correlation between the drug abusers accepting different dosages of methadone. Methods： The Questionnaire of Craving for Heroin, and QOL-BRIEF were used to measure the level of craving and quality of life when patients just entering the study and 6 months after treatment respectively. Results： ①The degree of craving decreased after 6 month treatment, espeeialy for the patients of high-dosage group. ②The QOLs of patietns had been improved after methadone treatment, but there was no difference between the different doseage group patients. ③There were negative correlations between craving and quality of life. The correlation coefficients were 0.451 and 0.450 and kept on steadily before and after treatment. Conclusion： High-dosage methadone can decrease craving. There is negative correlation between craving and quality of life.

关 键 词：美沙酮维持治疗 渴求 生存质量 

分 类 号：R395.2[哲学宗教—心理学]