雅安地区11家医院99例中药制剂不良反应报告分析  

Adverse Drug Reactions Induced by Chinese Drugs Preparations:Analysis of the Reports to 99 Cases from 11 Hospitals in Ya'an Region

作　　者：杨勤[1] 范岳邦 臧云吉 袁勇[1] 

机构地区：[1]四川雅安市人民医院药剂科,雅安市625000 [2]四川宝兴县人民医院,宝兴县625700

出　　处：《中国药房》2009年第18期1427-1429,共3页China Pharmacy

摘　　要：目的:调查雅安地区各医院使用中药制剂不良反应(ADR)的发生率、临床表现,探讨中药制剂的合理给药方案。方法:统计2008年1～12月期间,雅安地区各医院使用的中药制剂发生ADR的情况。结果:静脉滴注发生ADR为76.8%;ADR累及的系统/器官主要是皮肤及其附件,占31.3%;主要中药制剂品种为双黄连注射液,占18.3%;严重的ADR占4.0%。结论:应合理使用中药制剂,减少和避免ADR发生。OBJECTIVE： To investigate the incidence and clinical manifestations of adverse drug reactions （ADR）induced by Chinese drugs preparations in hospitals of Ya＇ an district and discuss the rational dosage regimen of Chinese drugs preparations. METHODS： The adverse drug reactions （ADR） induced by Chinese drugs preparations in hospitals of Ya＇ an district occurred from Jan. to Dec. in 2008 were analyzed statistically. RESULTS： The ADR induced by Chinese drugs preparations occurred via intravenous drip represented 76.8% of the total; lesions the skin and its appendages the major system-organ involved, represented 31.3% of the total; 18.3% were induced by Shuanghuanglian injections, and serious ADR accounted for 4.0%. CONCLUSION： It is important to use traditional medicine preparations rationally so as to reduce or avoid the incidence of ADR.

关 键 词：中药 注射液 药品不良反应 合理用药 

分 类 号：R969.3[医药卫生—药理学] R283[医药卫生—药学]