基于微扰蒙特卡罗的薄层状组织光学参数重构技术  

Reconstruction of Optical Properties of Thin Layered Tissue Based on Perturbation Monte Carlo Simulation

作　　者：赵会娟[1] 阎长斐[1] 张顺起[1] 关堂兵[1] 缪辉[1] 贺喜[1] 

机构地区：[1]天津大学精密仪器与光电子工程学院,天津300072

出　　处：《纳米技术与精密工程》2009年第3期254-258,共5页Nanotechnology and Precision Engineering

基　　金：国家自然科学基金资助项目(6067804960578008);国家重点基础研究发展计划(973)项目(2006CB705700)

摘　　要：针对层状组织体的光学参数(吸收系数和散射系数)快速重构问题展开讨论.发展了基于漫反射测量的适合于胃、宫颈等内脏薄层状组织光学参数重构的微扰蒙特卡罗模拟.数值模拟结果显示,该方法能够有效地利用漫反射光强重构临床应用范围内的光学参数,对单层模拟体的吸收系数和散射系数的重构误差均不大于±3%,对双层模拟体的重构误差小于10%,且两参数的重构之间几乎没有互扰.使用固体模型对上述算法进行的实验显示,重构出的散射参数与真值的误差小于±10%.进行一组光学参数重构耗时不超过1 min.结果表明,该方法可快速、准确地重构光学参数,为内脏器官近红外早期癌症诊断的临床应用提供保障.This paper aims at the development of rapid reconstruction of optical properties （ the absorption and scattering coefficients） based on the intensity of reflected diffused light. Perturbation Monte-Carlo model for the reconstruction of the optical properties of thin layered tissue, such as the stomatch and cervix, was evaluated with simulation data. Simulation results show that the proposed method is valid for the clinical range of optical properties. The reconstruction error for the reconstruction of the optical properties is less than ±3% and 10% for single and double layers, respectively. No crosstalk between the reconstructions of the two parameters was found. Experimental demonstration based on solid phantoms shows that the reconstructed scattering coefficient deviates from the ＂true value＂ by no more than ±10%. Reconstructing one set of optical properties takes less than I rain. The results show that the method can quickly and accurately reconstruct optical paramaters, thus providing a guarantee for the internal organs＇ near infrared early clinical diagnosis of cancer.

关 键 词：微扰蒙特卡罗模拟 光学参数重构 漫反射 混浊介质 

分 类 号：O435.1[机械工程—光学工程]