N-甲基苯胺和N,N-二甲基苯胺合成研究进展  

Progresses on Synthesis of N-methylaniline and N,N-dimethylaniline

作　　者：徐龙[1] 祝一锋[1,2] 李小年[1] 

机构地区：[1]浙江工业大学工业催化研究所绿色化学合成技术国家重点实验室培育基地,杭州310032 [2]浙江工业大学浙西分校,浙江衢州324000

出　　处：《化工生产与技术》2009年第3期30-33,41,共5页Chemical Production and Technology

摘　　要：基于苯胺N-甲基化反应在苯胺N-烷基化反应系列中的特殊性,介绍了近年来涉及合成N-甲基苯胺和N,N-二甲基苯胺的重要研究进展,分别对气相法和液相法制备N-甲基苯胺和N,N-二甲基苯胺的合成工艺进行了分析。认为液相法N-甲基化反应具有反应工艺路线可变性好、可通过耦合等方法来弥补其不足之处,具有一定的研究前景。而气相合成法还不具备完全取代液相合成法的优势。Based on the specialty of n-methylating, the recent progresses on synthesis of n-methylaniline and n,n-dimethylaniline were introduced, and the synthesis processes for n -methylaniline and n,n -dimethylaniline in gas -phase and liquid -phase are discussed, respectively. It was proposed that the n-methylating in liquid-phase was perspective because it had good changeability of synthesis route and the coupling method can compensate for its disadvantages. Whereas the gas-phase method was not advantageous enough to replace the liquid-phase method completely.

关 键 词：N-甲基苯胺 N N-二甲基苯胺 N-甲基化 进展 

分 类 号：TQ246.31[化学工程—有机化工]