二噁英类化合物对智力的影响  

Effects of Dioxin-Like Compounds on Intelligence

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作  者:吴景欢[1] 张建军[1] 

机构地区:[1]汕头大学医学院公共卫生与预防医学教研室,广东汕头515041

出  处:《环境与健康杂志》2009年第6期554-557,共4页Journal of Environment and Health

基  金:广东省自然科学基金资助项目(05301076)

摘  要:二噁英类化合物是一类持久性有机污染物,由于其高毒性、稳定性和生物蓄积性,对人类健康和环境具有严重危害。目前对二噁英的毒性研究已经涉及生殖毒性、免疫毒性、致癌性、内分泌毒性等多方面,但对其影响智力方面的研究较少。笔者从动物实验、人群调查方面综述了国内外有关二英与智力关系的研究,并分析了其可能机制。Dioxin-like compounds are a class of persistent organic pollutants (POPs). Because of their high toxicity, stability and bioaccumulation, they have serious effects on human health and environment. Studies on the toxicity of dioxins have involved in many aspects, such as reproduction toxicity, immune toxicity, carcinogenicity, endocrine toxicity, and so on. However, few studies of the effects on intelligence had been done, and its potential mechanism had not been reported till now. In this review, the authors tried to generalize the relationship between dioxins and intelligence based on animal behavioral tests and population investigations and hypothesize its potential mechanisms.

关 键 词:二噁英类化合物 智力 行为学实验 流行病学 

分 类 号:R994.6[医药卫生—毒理学]

 

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