生物材料在隆乳临床应用中的系统评价  

Evaluation of biomaterials in breast augmentation

作　　者：李斌[1] 张莹莹[2] 

机构地区：[1]沈阳市口腔医院美容整形科,辽宁省沈阳市11000 [2]沈阳美丽城美容医院,辽宁省沈阳市110002

出　　处：《中国组织工程研究与临床康复》2009年第25期4951-4954,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：目的:系统比较各种隆乳材料生物相容性及临床应用效果。方法:收集2004/2008CNKI数据库发表的有关隆乳材料方面的文献22篇。文章通过从隆乳材料,置入方式,临床效果,并发症处理难易程度及对机体的影响几方面对隆乳材料的临床应用进行评价;从距置入时间、置入体、并发症、原因及处理几方面分析了各种隆乳材料并发症;并从实验动物、实验分组、实验材料、观察方法、实验结果、实验结论方面整理分析,为临床应用提供了依据。结果:从4篇有关硅凝胶假体的动物实验中可以看出实验动物均是鼠、兔,实验结论均显示硅凝胶假体对人体免疫系统无较大影响,无细胞毒性,组织相容性良好,无致癌性,是较理想的隆乳材料。从18篇隆乳材料的临床应用中选出14篇,从中可以显示硅凝胶假体在生物医学材料的特性,手术操作及植入并发症等方面优于其他材料。结论:硅凝胶假体是一种良好的隆乳材料,组织相容性和细胞毒性良好。OBJECTIVE： To compare biocompatibility and clinical application effect of various biomaterials for breast augmentation. METHODS： A total of 22 articles about biomaterials for breast augmentation were collected from CNKI from 2004 to 2008. The clinical application of biomatedals was evaluated based on biomaterial collection, approaching way, clinical effect, complication processing, and organic effect; the complication was analyzed based on approaching time, implants, courses, and processing; thereafter, the references were sorted according to experimental animal, grouping, materials, observational method, results, and conclusions, which provided evidences for clinical application. RESULTS： Four articles about experimental animals, including rat and rabbit, indicated that silicone gel prosthesis did not have any effect on human immune system, while it did not have cytotoxicity and carcinogenicity but had well histocompatibility; therefore it was an ideal material for breast augmentation. A total of 14 out of 18 articles about clinical application of materials for breast augmentation demonstrated that silicone gel prosthesis was superior to other biomaterials in biomedical characteristics, surgical processing, and complication of implant. CONCLUSION： Silicone gel prosthesis is a good material for breast augmentation with well histocompatibility and cytotoxicity.

关 键 词：隆乳材料 硅凝胶假体 生物相容性 

分 类 号：R318[医药卫生—生物医学工程]