瑞芬太尼复合氯胺酮在小儿短小手术中的应用  

Application of compound of remifentanil with ketamine in clinical quick and minor anesthesia of children

作　　者：舒运兵[1] 孙广运[1] 杨晓慧[2] 

机构地区：[1]宜宾市第一人民医院,四川宜宾644000 [2]成都医学院附属宜宾医院,四川宜宾644000

出　　处：《四川医学》2009年第6期893-894,共2页Sichuan Medical Journal

摘　　要：目的观察瑞芬太尼（REM）复合氯胺酮在小儿短小手术中的临床应用。方法75例小儿短小手术患儿随机分为两组，氯胺酮复合瑞芬太尼组（KR组）35例，氯胺酮组（K组）40例。诱导均采用氯胺酮1.5-2mg／kg静脉给药，K组采用间断推注氯胺酮维持，追加剂量约为诱导剂量的1／3-1／2；KR组手术开始后立即静脉持续泵注瑞芬太尼O.01-1μg/（kg·min）维持，必要时追加氯胺酮。重点观察麻醉效果、定向力恢复砭不良反应。结果KR组与K组相比麻醉满意度、定向力恢复及不良反应，差异有统计学意义（P〈0.05）。结论KR组麻醉效能较K组可靠、安全，而呼吸抑制的发生率机会均等。Objective Observe the clinical application of Compound of Remifentanil （REM） with Ketamine in quick and minor anesthesia of children. Methods 75 quick and minor operations of children were randomized into the two groups： group KR （35 cases with Compound of remifentanil with ketamine） and group K （40 cases with ketamine ）. Ketamine was a-dopted as inducer by means of Ⅳ 1.5-2mg/kg, meanwhile ketamine was discontinuously used to keep the effect in group K and 1/3-1/2 of the inducer was added, while in group KR remifuntanil was pumped by means of Ⅳ 1.5 -2mg/kg immediately after the operation was started and ketamine was added when necessary. The anesthetic outcome, recovery of orientation and side effects were observed. Results Compared with group K, group KR was more superior in anesthetic satisfactory degree, orientatiun recovery and side effects（P〈0.05）. Conclusion The anesthetic effect of group KR is more reliable and safer than group K and the two group have the same possibility of respiratory depression.

关 键 词：瑞芬太尼 氯胺酮 小儿 短小手术 

分 类 号：R726.1[医药卫生—儿科]