手工法、半自动和全自动凝血仪测定凝血酶原时间的比较  

Comparison between automatic,semi-automatic analyzer and manual procedure for determination of prothrombin time

作　　者：林养[1] 吴春芳[1] 林荣华[1] 陈梅[1] 

机构地区：[1]广东省湛江市第四人民医院,524008

出　　处：《检验医学与临床》2009年第13期1039-1039,1041,共2页Laboratory Medicine and Clinic

摘　　要：目的研究不同方法测定凝血酶原时间的差别。方法采用手工法、半自动和全自动凝血仪检测相同的血浆标本,以凝固时间(PTT)、实验标本PTT值/健康对照PTT值(PTR)和国际标准化比值(INR)3项指标进行比较。结果用手工法、半自动和全自动凝血仪PTT值逐步缩短,差异有统计学意义(P<0.01);PTR和INR值用3种方法检测其结果基本一致,差异无统计学意义(P>0.05)。结论不同方法检测的PTT值差异有统计学意义,PTR和INR值差异无统计学意义,应当建立自己实验室的参考值,以校准PTT的差异。Objective To study the difference of prothrombin time determined by automatic, semi-automatic analyzer and manual proce-dure. Methods PTT,PTR,and INR were measured by automatic,semi-automatic analyzer and manual procedure. Results PTT value bacame shorter and shorter in manual way,and the difference is of statis- tic value. There was no difference in PTR and INR between the three ways. Conclusion There is different impovtance in PTT measurement by automatic, semi-automatic analyzer and manual ways, but no difference in PTR and INR measurement.

关 键 词：凝血酶原时间 方法学 影响因素 

分 类 号：R446[医药卫生—诊断学]