吉林省边境地区健康人群脊髓灰质炎中和抗体水平的监测  

Surveillance on Poliomyelitis Neutralization Antibody Level in the Border Areas in Jilin Province

作　　者：刘桂艳[1] 王丽霞[2] 常新[1] 吴丹[2] 曹迎春 陈超[1] 周剑惠[1] 王爽[1] 

机构地区：[1]吉林省疾病预防控制中心,长春130062 [2]白城市疾病预防控制中心,吉林白城137000

出　　处：《中国疫苗和免疫》2009年第3期249-250,共2页Chinese Journal of Vaccines and Immunization

摘　　要：目的了解吉林省边境地区健康人群脊髓灰质炎(脊灰)中和抗体水平。方法263份血清标本来自珲春、临江、集安市的<1岁、1～2岁、3～4岁、5～6岁、7～14岁、15～19岁、≥20岁人群,采用微量中和试验检测脊灰抗体。结果各年龄组健康人群I、Ⅱ、Ⅲ型脊灰中和抗体阳性率分别为94.98%、94.59%、92.28%,几何平均滴度分别为1:40.53、1:29.68、1:20.71,且随年龄增长呈下降趋势。结论吉林省边境地区健康人群,特别是<15岁儿童已形成良好的脊灰免疫屏障。Objective This project is designed for understand poliomyelitis （Polio） neutralization antibody level in the the border areas in Jilin province. Method 263 serum samples were collected from age groups of under l year old, 1-2,3-4,5-6,7-14,15-19 and above 20 years old. Microplate neutralization test was used to determine antibody level. Result Positive rates of neutralization antibody against Polio type Ⅰ,Ⅱ,Ⅲ were 94.98%, 94.59%, 92.28%. The geometric mean titre of Polio type Ⅰ,Ⅱ,Ⅲ were 1：40.53,1：29.68,1：20.71 respectively, which was decreased with the age increasing. Conclusion The population especially the population under 15 years old lived in places that near the border in Jilin province had good immunity barriar against poliomyelitis.

关 键 词：脊髓灰质炎 中和抗体 监测 

分 类 号：R512.4[医药卫生—内科学]