彩色多普勒血流定量技术评价系统性红斑狼疮患者肾皮质血流  

Quantitative color Doppler sonography assessment of the blood flow in renal cortex in patients with systemic lupus erythematosus

作　　者：陈玉媛[1] 张艳容[1] 王新房[1] 谢明星[1] 吕清[1] 严天慰[1] 鲁成发[1] 李薇玢[1] 项飞翔[1] 刘莹莹[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院超声科,湖北省分子影像中心重点实验室,湖北武汉430022

出　　处：《中国介入影像与治疗学》2009年第4期359-362,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的探讨多普勒超声血流定量技术评价系统性红斑狼疮(SLE)患者肾脏皮质血流灌注的临床价值。方法选取SLE患者21例(SLE组),22名健康人作为正常对照组。采用Philips IU22超声诊断仪测量肾叶间动脉、小叶间动脉阻力指数(RI);以定量分析软件计算反映肾脏皮质血流灌注的各项指数:血管指数(VI)、血流指数(FI)和血管-血流指数(VFI)。并对SLE组与正常对照组各指标进行比较分析。结果SLE患者肾皮质彩色血流信号较对照组稀疏,血流束纤细,到达皮质边缘的彩色血流信号较正常组减少;SLE患者叶间动脉、小叶间动脉RI值与正常对照组差异无统计学意义(P>0.05),VI、FI、VFI值均低于正常对照组,差异有统计学意义(VI、VFI,P<0.01;FI,P=0.01)。结论SLE患者的肾血流灌注显著低于正常对照组;彩色多普勒超声血流定量技术为诊断SLE肾损害提供了一种便捷、实时、无创的新方法。Objective To assess the value of quantitative color Doppler sonography in patients with systemic lupus erythematosus （SLE）. Methods The right renal in 21 patients with SLE and 22 normal subjects were examined with Philips IU22 ultrasonic diagnostic device. Resistence index （RI） of interlobar artery and interlobular artery were measured with color Doppler sonography, vascularity index （VI）, flow index （FI） and vascularization flow index （VFI） which reflecting the renal cortical blood flow were calculated with quantitated analysis software. All the parameters between two groups were compared and analyzed. Results The color signals of renal cortical blood flow in patients with SLE were inferior to those of the normal group, especially in the area near the edge of renal. No statistical difference of RI was found between the two groups （P〉0.05）, while VI, FI and VFI in SLE group were significantly lower than those of the normal group （VI, VFI, P〈0.01, FI, P=0.01）. Conclusion Color Doppler sonography combined with blood flow quantitative technique provide a helpful, sensitive and convenient tool to detecte the renal changes in SLE patients.

关 键 词：血流定量检测 超声检查 多普勒 彩色 系统性红斑狼疮 

分 类 号：R445.1[医药卫生—影像医学与核医学] R593.241[医药卫生—诊断学]