手性氨基烷基酚的合成及其绝对构型的确定  

The Synthesis and Confirmation of the Absolute Configuration of Chiral Aminoalkylphenol

作　　者：张兴刚[1] 刘镇[1] 王鑫[1] 张广友[1] 钱振旺 朱传武 

机构地区：[1]济南大学化学化工学院,山东济南250022 [2]山东济南泰飞科技有限公司,山东济南250033

出　　处：《山东化工》2009年第6期11-13,共3页Shandong Chemical Industry

摘　　要：合成了新型催化剂(1S,2R)-1-{[(1R)-1-(2-羟基-5-甲基苯基)乙基]氨基}-2-茚满醇,其结构通过IR、1HNMR和元素分析得到证实。绝对构型通过对其单晶的X-射线衍射结果分析,确定了新化合物的绝对构型为(S,R,R)。Novelcataly（1S,2R） - 1 - { [ （1R） - 1 - （2 - hydroxy - 5 - methylphenyl） ethyl] amino } indan-2- oi, has been synthesized and structures of compounds were confirmed by IR, 1H NMR and element analysis. The absolute structures of the compounds were confirmed by the analysis on X - ray crystal structure . The new stereogenic center was unambiguously determined to have an （S, R, R） configuration.

关 键 词：催化剂 手性氨基烷基酚 单晶 X射线衍射 绝对构型 

分 类 号：O625.634[理学—有机化学]