Effects of Collagen Peptide from Cyanea nozakii on Mouse Immune Function  

霞水母胶原蛋白活性肽对小鼠免疫功能的影响(英文)

作　　者：邓超 汤鲁宏 陈伟[1] 王琪 林丹 

机构地区：[1]江南大学医药学院

出　　处：《Agricultural Science & Technology》2009年第2期118-121,共4页农业科学与技术（英文版）

基　　金：国家农业科技成果转化资金项目(2007GB2C100105)~~

摘　　要：[Objective ] The study aimed to provide a theoretical basis for the clinical application of collagen peptide from Cyanea nozakii. [ Method] After acute toxicity test on mice, collagen peptide from C. nozakii were given to mice by continuous intragastric administration for 30 d at the doses of 25, 50, 100 mg/kg, and then the phagocytosis of macrophage, delayed type hypersensitivity （DTH） and serum hemolysin level were determined. [ Result] Collagen peptide from C. nozakii was atoxic or low toxic, and the three immune indices of experimental groups were signifi- canUy higher than those of the control group （treated with same volume of normal saline） at 0.05 or 0.01 level. E Conclusion] Collagen peptide from C. nozakii has a certain immunopotentiation.1材料与方法1．1材料1．1．1霞水母胶原蛋白活性肽。由霞水母酶解提取、经冷冻干燥得到，为淡棕色粉末。由江南大学医药学院药物化学与药物分析实验室制备（具体方法参见已向国家申请的专利200710171188．6）。

关 键 词：Cyanea nozakii Collagen peptide IMMUNOPOTENTIATION 

分 类 号：S859.1[农业科学—临床兽医学]