阿托伐他汀对急性脑梗死患者血清高敏C反应蛋白及血脂的影响  

Effect of Therapy with Atorvastatin on High Sensitivity C-reactive Protein and Blood Lipid with Acute Cerebral Infarction

作　　者：顾力华[1] 姜丽芸[1] 任亢宗[1] 

机构地区：[1]云南省昆明市中医医院急诊科,昆明650032

出　　处：《中国医药导刊》2009年第5期792-793,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:观察阿托伐他汀对急性脑梗死患者高敏C-反应蛋白及血脂的影响。方法:将86例急性脑梗死患者随机分为治疗组和对照组,治疗组给予常规治疗及口服阿托伐他汀片20 mg,口服,1次/日,疗程8周;对照组只给予常规治疗。分别在治疗前后观察两组患者血清高敏C-反应蛋白及血脂浓度的变化情况。结果:经治疗后,治疗组患者血清高敏C-反应蛋白、总胆固醇、甘油三脂、低密度脂蛋白显著降低,高密度脂蛋白升高。与对照组相比具有显著性差异(P<0.05)。结论:阿托伐他汀能够降低急性脑梗死患者高敏C-反应蛋白,并具有良好的调脂作用。Objective： To explore the effect of atnrvastatin on high sensitivity C-reactive protein and blood lipid in patients with acute cerebral infarction. Methods：Eighty six cases of acute cerebral infraction were randomly divided into atorvastatin group（ 10mg atorvastatin per day, n = 45 ） and control group（ n = 41 ）. The levels of high sensitivity C-reactive protein and blood lipid were tested before and eight week after therapy. Results：The levels of h-CRP,cholestevol, triglyeerides and LDL-C were decreased significantly and the levels of HDL-C increased after atorvastatin therapy. Conclusion ：Atorvastatin can decrease high sensitivity C-reactive protein and blood lipid and reduce the risk of acute cerebral vascular disease.

关 键 词：阿托伐他汀 急性脑梗死 高敏C-反应蛋白 血脂 

分 类 号：R969[医药卫生—药理学]