回声跟踪技术评价高脂血症、高血压病、动脉粥样硬化患者颈动脉功能  

EVALUATION OF CAROTID ARTERY FUNCTION IN PATIENTS WITH HYPERLIPIDEMIA,HYPERTENSION AND ATHEROSCLEROSIS BY ECHO-TRACKING TECHNIQUE

作　　者：郭华莉 刘天虎[1] 褚洪毅 李霞[1] 王宏宇[2] 刘淑华[3] 

机构地区：[1]郫县人民医院心内科,郫县611730 [2]北京大学人民医院 [3]四川大学华西医院

出　　处：《现代预防医学》2009年第13期2550-2552,共3页Modern Preventive Medicine

基　　金：卫生部十年百项计划"血管病变早期检测技术推广"项目资助(04-10-01)

摘　　要：[目的]评价高脂血症、高血压病、动脉粥样硬化患者颈动脉弹性功能变化。[方法]运用血管回声跟踪技术检测高脂血症组、高血压病组、动脉粥样硬化组和正常对照组的颈总动脉弹性参数,包括压力应变弹性系数(Ep)、僵硬系数(β)、动脉顺应性(AC)、脉搏波放大指数(AI)、脉搏波传导速度(PWVβ),并进行评价分析。[结果]和正常对照组比较,高脂血症组、高血压病组的Ep、β值、AI、PWVβ增高显著,AC显著降低(P﹤0.05)。和正常对照组比较,动脉粥样硬化组的Ep、β值、AI、PWVβ增高非常显著,AC降低非常显著(P﹤0.01)。和高脂血症组、高血压病组比较,动脉粥样硬化组的Ep、β值、AI、PWVβ增高显著,AC显著降低(P﹤0.05)。[结论]血管回声跟踪技术可以早期、准确、方便的评价高脂血症、高血压病和动脉粥样硬化患者的动脉弹性功能,高脂血症、高血压病和动脉粥样硬化患者的颈总动脉弹性功能明显降低。[Objective] To evaluate the change of carotid artery function by echo-tracking technique in patients with hyperlipidemia, hypertension and atherosclerosis. [Methods] A total of 1 160 cases were divided into four groups： normal control group （40 cases）, hyperlipidcmia group （40 cases）, hypertension group （40 cases）, and atherosclerosis group （40 cases）. The changes of carotid artery fimction were evaluated by echo-tracking technique. [ Results] Pressure elastic coefficient （Ep） was significantly higher in patients with hyperlipidemia, hypertension and atherosclerosis than tllat of normal subjects （ 133.61±33.89 VS 111.33±32.03, P 〈 0.05; 192.23±45.88 VS 111.33±32.03, P 〈 0.01 ; 222.17±75.13 VS 111.33±32.03, P 〈 0.001, respectively） .Stiffness parameter （13） was significantly higher in patients with hyperlipidemia, hypertension and atherosclerosis than that of normal subjects （ 10.68±1.71 VS 8.21±2.19, P 〈 0.05; 12.36±3.02 VS 8.21 ±2.19, P 〈 0.001 ; 15.36±4.46 VS 8.21±2,19, P 〈 0.001, respectively）. Arteo＇ compliance （AC） was significantly lower in patients with hyperlipidemia, hypertension and atherosclerosis than that of normal subjects （0.62±0.16 VS 0.75±0.24, P 〈 0.05; 0.51±0.11 VS 0.75.±0.24, P 〈 0.001 ; 0.46±0. 07 VS 0.75±0.24, P 〈 0.001, respectively）. Augmentation index （AI） was significantly higher in patients with hyperlipidemia, hypertension and atheroselerosis than that of normal subjects （17.34±9.50 VS 12.78±5.94, P 〈 0.05; 17.51±10.06 VS 12.78±5.94, P〈 0.05; 28.31±9.86 VS 12.78±5.94, P〈 0.001, respectively）. Pulse wave velocity （PWV13） was significantly higher in patients with hyperlipidemia, hypertension and atherosclerosis than that of normal subjects （7.05±0.93 VS 6.32±0.89, P 〈 0.05; 8.32±0.96 VS 6.32±0.89, P 〈 0.001; 11.25±1.89 VS 6.32.±0.89, P 〈 0.001, respectively） .The Ep, 13, AI and PWV13 were significantly higher in patients with atherosclerosis than that of hyperlipidemi

关 键 词：回声跟踪技术 超声检查 高脂血症 高血压病 动脉粥样硬化 

分 类 号：R445[医药卫生—影像医学与核医学] R544.1[医药卫生—诊断学]