冠心病患者检测sd-LDLc的临床意义  

The Clinical Significance of the Coronary Heart Disease Sufferer Detection sd-LDLc

作　　者：苏亚芬[1] 高冠宇[1] 黄乐[1] 董礼航[1] 王荣[1] 黄永麟[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院心血管研究室,黑龙江哈尔滨150001

出　　处：《现代生物医学进展》2009年第12期2297-2300,共4页Progress in Modern Biomedicine

摘　　要：目的:观察冠心病患者血浆小而密集低密度脂蛋白(sd-LDLc)水平,探讨sd-LDLc与冠状动脉粥样硬化的关系。方法:按照试验入选标准收集我院近年门诊或住院患者131例。其中,隐匿型57例,心绞痛型46例,心肌梗死型28例。应用美国贝克曼公司CX5全自动生化分析仪检测血浆sd-LDLc水平,观察各组间的sd-LDLc数值变化,结果进行相关统计学方法分析,了解sd-LDLc对冠心病的影响及临床意义。结果:sd-LDLc与冠状动脉粥样硬化的病变程度成正相关,(p<0.01)。结论:血浆sd-LDLc与冠状动脉粥样硬化有密切联系,对于预测冠心病的严重程度有一定的临床意义。Objective： To investigate the plasma level of small dense low-density lipoproteins （sd-LDL） in patients with coronary heart disease （CHD） and to explore roles of sd-LDL in CHD. Methods： We examined 131 patients with CHD in our clinic service and ad- mitring department according to the standard of research to be selected, including 57 cases of delitescence CHD, 46 cases of angina pec- toffs and 28 cases of myocardial infarction. The plasma level of sd-LDL was determined by automatic biochemistry analysator. All data were presented as the Mean _＋ SEM. Statistical calculations were performed on a personal computer using SPSS 10.0. Results： The plas- ma level of sd-LDL were positive ratio with the severity of CHD. Conclusion： Plasma level of sd-LDL was correlated with CHD and severity of CHD. The sd-LDL abnormality was important risk factor of CHD.

关 键 词：冠心病 小而密集低密度脂蛋白 粥样硬化 

分 类 号：R541.4[医药卫生—心血管疾病]