Electrical impedance scanning in breast tumor imaging： correlation with the growth pattern of lesion  

作　　者：WANG Kan WANG Ting FU Feng JI Zhen-yu LIU Rui-gang LIAO Qi-mei DONG Xiu-zhen 

机构地区：[1]Department of Medical Electronic Engineering, Faculty of Biomedical Engineering, the Fourth Military Medical University, Xi'an, Shaanxi 710032, China [2]Department of Endocrinology and Vascular Surgery, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi 710032, China

出　　处：《Chinese Medical Journal》2009年第13期1501-1506,共6页中华医学杂志（英文版）

基　　金：This work was supported in part by a grant from the National Natural Science Foundation of China （No. 50337020）.

摘　　要：Background This study researched the electric impedance properties of breast tissue and demonstrated the different characteristic of electrical impedance scanning （EIS） images. Methods The impedance character of 40 malignant tumors, 34 benign tumors and some normal breast tissue from 69 patients undergoing breast surgery was examined by EIS in vivo measurement and mammography screening, with a series of frequencies set between 100 Hz-100 kHz in the ex vivo spectroscopy measurement. Results Of the 39 patients with 40 malignant tumors, 24 showed bright spots, 11 showed dark areas in EIS and 5 showed no specific image. Of the 30 patients with 34 benign tumors there were almost no specific abnormality shown in the EIS results. Primary ex vivo spectroscopy experiments showed that the resistivity of various breast tissue take the following pattern： adipose tissue〉cancerous tissue〉mammary gland and benign tumor tissue. Conclusions There are significant differences in the electrical impedance properties between cancerous tissue and healthy tissue. The impedivity of benign tumor is lower, and is at the same level with that of the mammary glandular tissue. The distinct growth pattern of breast lesions determined the different electrical impedance characteristics in the EIS results.Background This study researched the electric impedance properties of breast tissue and demonstrated the different characteristic of electrical impedance scanning （EIS） images. Methods The impedance character of 40 malignant tumors, 34 benign tumors and some normal breast tissue from 69 patients undergoing breast surgery was examined by EIS in vivo measurement and mammography screening, with a series of frequencies set between 100 Hz-100 kHz in the ex vivo spectroscopy measurement. Results Of the 39 patients with 40 malignant tumors, 24 showed bright spots, 11 showed dark areas in EIS and 5 showed no specific image. Of the 30 patients with 34 benign tumors there were almost no specific abnormality shown in the EIS results. Primary ex vivo spectroscopy experiments showed that the resistivity of various breast tissue take the following pattern： adipose tissue〉cancerous tissue〉mammary gland and benign tumor tissue. Conclusions There are significant differences in the electrical impedance properties between cancerous tissue and healthy tissue. The impedivity of benign tumor is lower, and is at the same level with that of the mammary glandular tissue. The distinct growth pattern of breast lesions determined the different electrical impedance characteristics in the EIS results.

关 键 词：breast cancer impedance scanning spectroscopy measurement of breast 

分 类 号：S858.292[农业科学—临床兽医学] TS103.6[农业科学—兽医学]