心脏磁共振成像评价健康志愿者心脏的结构和功能  

Evaluation of Cardiac Structure and Function by Cardiac Magnetic Resonance Imaging in Healthy Volunteers

作　　者：周璐[1] 金征宇[1] 张竹花[1] 王怡宁[1] 孔令燕[1] 宋兰[1] 张立仁[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院放射科,北京100730

出　　处：《中国医学科学院学报》2009年第2期210-214,共5页Acta Academiae Medicinae Sinicae

摘　　要：目的探讨心脏磁共振(CMR)电影成像在评价左右心室结构和功能方面的作用。方法采用快速稳态平衡进动序列对36名健康志愿者进行CMR检查,用Report Card软件分析左右心室的结构和收缩功能,并分析CMR测量结果与超声心动图(UCG)测量结果的相关性。结果CMR电影成像显示左心室的室间隔厚度、后壁厚度、舒张末期内径和收缩末期内径分别为(9.2±2.1)、(8.0±2.1)、(48.6±5.5)和(30.3±5.3)mm,右心室的长径和短径、长径指数和短径指数分别为(69.2±9.7)和(30.6±6.6)mm、(39.4±5.5)和(18.1±3.4)mm/m2。上述左心室结构指标的测量结果与UCG的测量结果均呈正相关(r值分别为0.843,0.784,0.686,0.730,均P<0.01)。心功能分析显示左、右心室的舒张末期容积分别为(93.6±17.2)和(108.6±28.2)ml,收缩末期容积分别为(39.5±13.0)和(45.6±15.1)ml,射血分数分别为(58.5±8.19)%和(58.2±7.4)%。左心室射血分数CMR成像的结果与UCG(64.1±6.8)%呈正相关(r=0.75,P<0.01)。结论CMR电影成像技术结合标准平面定位能准确评价左右心室的结构和功能,尤其在评价右心室的结构和功能方面具有明显优势,可用于心脏疾病的诊断及疗效监测。Objective To evaluate the role of cardiac magnetic resonance （CMR） sequence in assessing the cardiac structure and function. Methods A total of 36 healthy volunteers were examined with fast imaging employing steady-state acquisition cine MR sequence. All the MR images were processed on Report Card software to test the cardiac dimensions and function. The relationships between the CMR results and the ultrasonic cardiography （UCG） results were analyzed. Results CMR analysis showed that interventricular septum thickness, left ventricle posterior wall thickness, end diastolic dimension of left ventricle, and end systolic dimension of left ventricle were （9.2 ± 2.1 ）, （8.0 ± 2.1 ） , （48.6 ± 5.5 ）, and （ 30.3 ± 5.3 ） mm, respectively. Major dimension of right ventricle, minor dimension of right ventricle, index of major, dimension of right ventricle and index of minor dimension of right ventricle were （ 69.2 ± 9.7 ）, （ 30.6 ± 6.6 ） mm, and （ 39.4 ± 5.5 ）, （ 18.1 ± 3.4 ） mm/m^2, respectively. The left ventricle indicators above measured by CMR correlated with those by UCG （ r = 0. 843, 0. 784, 0.686, 0. 730, all P 〈 0.01 ）. CMR analysis showed that left ventricular end diastolic volume, right ventricular end diastolic volume, left ventricular end systolic volume, and right ventficular end systolic volume were （93.6 ± 17.2）, （ 108.6 ±28.2） （39.5 ± 13.0）, and （45.6 ± 15.1 ） ml, respectively. The left ventricular ejection fraction and right ventricular ejection fraction were （58.5 ± 8.19 ） % and （ 58.2 ± 7.4 ） % , respectively. Left ventricular ejection fraction measured by CMR was correlated with that （64.1±6.8） % by UCG （r=0.75, P〈0.01）. Conclusions CMR sequence with standard location is well applicable for accurate measurement of left and fight ventricle dimensions and function, especially for right ventricle. CMR can be used to diagnose the heart disease and monitor the efficacy.

关 键 词：心脏磁共振 电影序列 心室结构功能 超声心动 

分 类 号：R81[医药卫生—放射医学]