急性心肌梗死超急期中医证型与血浆HCY、LDL-C的关系  

Relationship between TCM Syndrome Types and Plasma HCY,LDL-C in Hyperacute Period of Acute Myocardial Infarction

作　　者：张玲端[1] 王颖[1] 

机构地区：[1]郑州大学第一附属医院,郑州450052

出　　处：《中国中医急症》2009年第7期1105-1106,共2页Journal of Emergency in Traditional Chinese Medicine

摘　　要：目的观察急性心肌梗死超急期患者中医证型与血浆同型半胱氨酸(HCY)及低密度脂蛋白胆固醇(LDL-C)的关系。方法将184例患者按中医辨证分为气滞血瘀、气虚血瘀、阴阳两虚、阳虚寒凝四型,用荧光偏振免疫法检测急性心肌梗死超急期患者与健康对照组血浆HCY水平,并检测血脂水平。结果急性心肌梗死超急期患者血浆HCY水平显著高于健康对照组,气滞血瘀型血浆HCY及LDL-C水平显著高于健康对照组,且气滞血瘀型血浆HCY与LDL-C水平呈正相关。结论血浆HCY水平异常增高是急性心肌梗死超急期的重要危险因素之一,急性心肌梗死超急期患者血浆HCY及LDL-C水平显著增高且呈正相关可作为中医证型气虚血瘀型的辨证指标。Objective： To explore the relationship between TCM syndrome types and the plasma homocysteine （HCY） and low density lipoprotein cholesterol in hyperaeute period of acute myocardial infaretion（HPAMI） . Methods： 184 cases were divided into four syndromes： qi stagnation and blood stasis group, qi deficiency and blood stasis group, yin and yang deficiency group and yang deficiency and cold accumulation group. Plasma HCY and LDL-C in all patients were detected by fluorescence polarization immunoassay. Results： HCY level in patients of HPAMI was significantly higher than that of health controls. Meanwhile, levels of HCY and LDL-C in type qi stagnation and blood stasis of were significantly higher than those in health control. There was a positive correlation between HCY and LDL-C level. Conclusion： Abnormal increase of plasma HCY level is one of important risk factors of HPAMI. The significant increase and positive correlation of plasma HCY and LDL-C could be the differentiation index of qi deficiency and blood stasis type.

关 键 词：同型半胱氨酸 急性心肌梗死超急期 中医证型 血脂 

分 类 号：R542.22[医药卫生—心血管疾病]