胺碘酮与利多卡因在快速室性心律失常急性期治疗的比较  

Comparative study of Amiodarone and Lidocaine on fast ventricular arrhythmia during its acute period

作　　者：吴宇红[1] 郭念昆[1] 刘永丽[1] 

机构地区：[1]新疆医科大学第六附属医院心内科,新疆乌鲁木齐830002

出　　处：《新疆医科大学学报》2009年第6期711-713,共3页Journal of Xinjiang Medical University

摘　　要：目的:评价胺碘酮与利多卡因治疗快速室性心律失常急性期的疗效及安全性。方法:将130例患者分为胺碘酮治疗组70例,利多卡因治疗组60例,回顾比较两种药物对快速室性心律失常急性期的疗效、病死率、不良反应发生率。结果:在快速室性心律失常急性期治疗中,胺碘酮组优于利多卡因组(P=0.017),两组患者病死率差异无统计学意义(P=0.793),利多卡因组不良反应发生率低于胺碘酮组(P=0.037)。结论:胺碘酮是治疗快速室性心律失常急性期效果较好的药物,推荐作为首选药物。Objective： To evaluate the curative effect and security of Amiodarone and Lidocaine on arrhythmia in its acute period. Methods： 130 cases were divided into two groups as Amiodarone group with 70 cases and Lidocaine group with 60 cases. And the retrospective comparison and analysis of curative effect, mortality and adverse drug reactions of the two kind of medications on the treatment of fast ventricular arrhythmia in its acute period were performed. Results： On the treatment of fast ventricular arrhythmia during its acute period, Amiodarone was more effective than Lidocaine （P=0. 017）. And no statistical significance of mortality was obtained between these two groups. The incidence rate of adverse drug reactions were lower in Lidocaine group than the Amiodarone group （P =0.037）. Conclusion： Amiodarone relatively has a good curative effect on the treatment of fast ventricular arrhythmia during its acute period, and it could be recommended as the first choice for the treatment.

关 键 词：胺碘酮 利多卡因 快速室性心律失常 

分 类 号：R614.2[医药卫生—麻醉学] R541.7[医药卫生—外科学]