老年2型糖尿病患者胰高血糖素对血糖、血压变化的反应  

Response of glucagon to the changes of glucose and blood pressure in elderly patients with type 2 diabetes

作　　者：朱惠[1] 陆颖理[1] 张惠新[1] 夏芳珍[1] 顾婷[1] 陈奕[1] 叶婷婷[1] 杨华[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院内分泌科,200011

出　　处：《中华内分泌代谢杂志》2009年第3期295-296,共2页Chinese Journal of Endocrinology and Metabolism

摘　　要：检测71例老年2型糖尿病患者胰高血糖素对血糖变化的反应及其与血压之间的关系。结果显示，餐后血糖增加值〈2．5mmol/L组与≥2．5mmol／L组相比，胰高血糖素的增加值明显高于后者（P〈0．05）；血压正常组与高血压组相比，餐后胰高血糖素增加值也明显升高（P〈0．05）。提示老年2型糖尿病患者胰高血糖素对血糖变化反应性下降与血糖和血压升高有关。The response of glucagon to the change of glucose and its relation to blood pressure in 71 eldely patients with type 2 diabetes was investigated. The results showed that the postprandial increment of glucagon in the group of patients with postprandial 2h plasma glucose increment〈2.5 mmol/L was significantly higher than that in the group with plasma glucose increments〉 2.5 mmol/L （ P〈0.05 ）. The postprandial increment of glucagon in patients with normal blood pressure was significantly higher than that in patients with hypertension （ P〈0.05 ）. The results suggest that the decreased response of glucagon to the change in plasma gluense in elderly patients with type 2 diabetes is related to increased blood glucose and high blood pressure.

关 键 词：胰升糖素 糖尿病 2型 高血压 

分 类 号：R587.1[医药卫生—内分泌] R556.5[医药卫生—内科学]