重组人p53腺病毒注射液治疗颈部肿瘤30例疗效观察  

Treatment of 30 neck tumor cases with recombinant adenovirus p53

作　　者：陈英赛[1] 陈娇燕[1] 王丽萍[1] 周桂梅[1] 

机构地区：[1]海南省人民医院放疗科,海南海口570311

出　　处：《海南医学院学报》2009年第8期881-882,886,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020090086)~~

摘　　要：目的:观察重组人p53腺病毒注射液治疗颈部肿瘤的可行性。方法:鼻咽癌颈部肿瘤患者60例分为观察组与对照组,每组30例,两组患者均接受放疗,观察组给予重组人p53腺病毒注射液,对两组患者进行一定护理。结果:观察组显效率为70%,有效率为30%。对照组显效率为17%,有效率为63%,两组比较差异有统计学意义(P<0.05)。结论:通过重组人p53腺病毒注射液治疗颈部肿瘤,进行心理护理、健康教育等正确的护理措施,使患者积极主动配合治疗,保证了治疗计划顺利进行,提高了中晚期鼻咽癌患者的治疗疗效和生存率。Objective： To explore the availability of treatment of neck tumor with recombinant adenovirus p53 injection. Methods： Randomly separated 60 eases with nasopharyngeal carcinoma into observation group and control group with 30 cases per group. Employed radiotherapy and nursing to all patients, and gave cases in observation group with recombinant adenovirus p53 injection. Results： Obvious efficacy rate was 70% and efficacy rate was 30% in observation group; while obvious efficacy rate was 17% and efficacy rate was 63% in control group, with significant difference between two groups （P 〈 0.05）. Conclusion ： Recombinant adenovirus p53 injection combined with physiological nursing, health education and appropriate nursing can promote cooperation from patients, guarantee treatment process and boost the effect and survival rate.

关 键 词：重组人p53病毒注射液 颈部肿瘤 护理 

分 类 号：R373.1[医药卫生—病原生物学] R394.2[医药卫生—基础医学]