抗感染药致药疹734例分析  

Analysis of 734 cases of dermatitis medicamentosa caused by antiinfectious drugs

作　　者：周劲松[1] 李世荫[1] 

机构地区：[1]北京医科大学第三医院皮肤科

出　　处：《临床皮肤科杂志》1998年第4期224-226,共3页Journal of Clinical Dermatology

摘　　要：对诊断确切的由抗感染药引起的药疹７３４例，采用临床与试验相结合的方法确认其致病药物，在此基础上对其疹型及致病药物种类进行了分析。发疹型药疹最为常见，其次为固定性红斑和荨麻疹与血管性水肿。过敏性休克或全身过敏症多见于用β内酰胺族药物之后，固定性红斑多见于用磺胺类之后。致病药物中β内酰胺族最常见，其次为磺胺类。硝基呋喃类、四环素类、氨基糖甙类及喹诺酮类亦较常见。cases of drug eruption caused by antimicrobial drugs used today were analysed. It showed that the most common form among them was exanthematous type, secondly were fixed eruption and urticaria angioedema types. Allergic shock and anaphylaxis often occured after the use of β lactam antibiotics. fixed eruptin often occured after the use often occured after the use of β lactam antibiotics.Fixed eruption often occured after the use of sulfa drugs. The most common causative drug were β lactam antibiotics. Sulfa deugs were the second. Nitrofurans, tetracyclines, aminoglycosides and quinolones were also commonly encountered.

关 键 词：药物性皮炎 抗感染药 病因 临床分析 

分 类 号：R758.250.2[医药卫生—皮肤病学与性病学]