急性颅脑损伤患者心电图QT离散度的特点与意义  

Changes and significance of the QT dispersion in acute brain injuries

作　　者：张利环[1] 杜凤和[1] 

机构地区：[1]首都医科大学北京天坛医院,北京100050

出　　处：《山东医药》2009年第21期8-9,共2页Shandong Medical Journal

基　　金：国家自然科学基金资助项目(C03030201)

摘　　要：目的探讨急性颅脑损伤(ABI)患者心电图QT、JT间期变化对其轻重程度的判断及预后评估的意义。方法根据格拉斯哥昏迷评分,将101例ABI患者分为轻、中、重型三组;根据患者有无蛛网膜下腔出血(SAH),分为SAH组及无SAH组。检测各组伤后24 h内心电图的QT间期及JT间期,计算QT离散度(QTd)、校正的QT离散度(QTcd)、JT离散度(JTd)及校正的JT离散度(JTcd);根据格拉斯哥预后评分判断预后,对其不同组间的各值进行统计学分析。结果轻、中、重型ABI患者的心电图QTd、QTcd、JTd、JTcd存在显著性差异,且SAH组各指标均升高,较无SAH组有显著统计学差异(P<0.01或<0.05),并与预后有明显的相关性(P均<0.01)。结论QTd、QTcd、JTd、JTcd对判断ABI程度及其预后评估有重要参考价值,可作为预测患者临床转归的指标,并且有助于早期临床干预。Objective To investigate the acute brain injuries of the QT, JT interval, and evaluate their effect on the severity and prognosis. Methods One hundred and one patients were divided into three groups according to the GCS score, namely light, middle and heavy group, they were divided into subarachnoid hemorrhage group and without subarachnoid hemorrhage group. The QT interval. JT interval. QT dispersion, corrected QT dispersion. JT dispersion and corrected JT dispersion within 24 h after injury were detected; prognosis was estimated by gas score. All values in different group were analyzed statistically. Results The more the severity of brain injury, the longer of the QTd, QTcd. JTd, JTed, especially in patients with subarachnoid hemorrhage （ P 〈 0.01, 〈 0.05）, and related to the prognosis. Conclusions QTd, QTcd, JTd. JTcd have important reference value. It can act as index to predict clinical turnover and help to early clinical intervention.

关 键 词：颅脑损伤 急性 蛛网膜下腔出血 QT间期离散度 JT间期离散度 

分 类 号：R651[医药卫生—外科学]