石墨炉原子吸收法测定苏氨酸中微量砷  

Determination of Trace Arsenic in Threonine by GFAAS

作　　者：周蓓瀛[1] 李楠[2] 郄冰冰[3] 郭瑞锋[3] 毕雪艳 

机构地区：[1]冀中能源峰峰集团总医院药剂科,河北邯郸056200 [2]河北省邯郸市铁路医院,河北邯郸056001 [3]河北省药品检验所,河北邯郸050011 [4]河北省邯郸市药品检验所,河北邯郸056001

出　　处：《中国药业》2009年第14期37-38,共2页China Pharmaceuticals

摘　　要：目的采用石墨炉原子吸收法测定苏氨酸中微量砷。方法检测波长为193.7nm,灯电流为12.0mA,狭缝宽度为1.3nm。结果砷质量浓度在1.0000～50.0000μg/L范围内与吸光度线性关系良好,r=0.9994,平均加样回收率为98.31%,RSD=0.6%(n=9)。结论石墨炉原子吸收法能有效控制苏氨酸的质量,且简单、准确、灵敏。Objective To establish the graphite furnace atomic absorption spectrometry （GFAAS） method for the determination of trace arsenic（As） in threonine. Methods The determined wavelength was at 193.7 nm, the electric current of the light was 12.0 mA, the slitwidth was 1.3 nm. Results The good linear relation was showed in the range of 1. 000 0- 50. 000 0 μg/L for arsenic by GFAAS with the regression coefficient of 0. 999 4. The average recovery rate was 98.31%, RSD =0. 6% （n =9）. Conclusion The method is simple, accurate and sensitive, which can be effectively used for controlling the quality of threonine.

关 键 词：苏氨酸 砷 石墨炉原子吸收法 

分 类 号：R927.2[医药卫生—药学] R977.4