调糖饮对2型糖尿病胰岛素抵抗及血清脂联素的影响  

Influence of Tiaotangyin on Insulin Resistance and Serum Adiponectin in Type Ⅱ Diabetes Mellitus

作　　者：马宁宁[1] 方兆东[2] 

机构地区：[1]广西中医学院 [2]广西中医学院附属瑞康医院,530011

出　　处：《广西中医药》2009年第3期5-7,共3页Guangxi Journal of Traditional Chinese Medicine

基　　金：广西研究生教育创新计划资助项目(2008106001008M14)

摘　　要：目的:观察调糖饮对2型糖尿病胰岛素抵抗及血清脂联素的影响。方法:将纳入的90例患者,随机分为A、B、C组各30例,另随机选取健康受试者30人作为空白对照组。在糖尿病基础治疗基础上,A组予调糖饮胶囊,B组予二甲双胍片,C组予调糖饮胶囊合二甲双胍片,三组疗程均为3个月。治疗前后测定FPG、UA、TC、TG、HDL-C、LDL-C、脂联素并进行比较。结果:A、B、C组治疗3个月后,FPG、HOMA-IR及血脂、脂联素、尿酸等实验室指标均有显著改善(P<0.05或P<0.01),其中以C组改善程度最显著。结论:调糖饮有调节糖、脂代谢紊乱,并有改善胰岛素抵抗的作用,可能与其提高血清脂联素水平有关。Objective： To observe the influence of Tiaotangyin on insulin resistance and serum adiponectin in type Ⅱ diabetes mellitus. Methods： Ninety cases with type Ⅱ diabetes mellitus were randomly divided into three groups： A, B, C. each group with 30 eases. Other 30 healthy volunteers were randomly selected as blank group. Besides basic diabetes treatments, group A was given Tiaotangyin capsules, group B was given melbine tablets, group C was given both Tiaotangyin capsules and melbine tablets, the treatment of all these three groups was three months. The FPG, UA, TC, TG, HDL-C, LDL-C, adiponectin were tested and compared pre and post treatment. Results： After three months treatment, FPG, HOMA-IR, blood fat, adiponectin, uric acid and other laboratory index were improved significantly （P〈0.05 or P〈0.01 ） in A, B, C group, and group C has the most significant improvement. Conclusions： Tiaotangyin has the effects of adjusting glycolipid metabolic disorder, improving insulin resistance, it may relate to its function of improving serum adiponectin.

关 键 词：调糖饮 胰岛素抵抗 脂联素 

分 类 号：R255.4[医药卫生—中医内科学]