药物洗脱支架与金属支架生物相容性比较及支架置入后的血管再狭窄  

Biocompatibility of drug-eluting stent versus bare metal stent in treating coronary artery disease and vascular restenosis following stent implantation

作　　者：李乐雯 张艳[1] 习隽丽[1] 王家昆[1] 贝筝 吴瑞[1] 

机构地区：[1]海南省干部疗养院,海南省海口市571100

出　　处：《中国组织工程研究与临床康复》2009年第26期5125-5128,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：药物洗脱支架与裸金属支架相比,最大的改进就是在原有裸金属支架平台上,增加了药物载体和药物。虽然冠状动脉支架的成功率和安全性有了提高,但是再狭窄仍然是限制支架应用的一个障碍。药物洗脱支架置入后的过敏反应已有报道。文章在药物洗脱支架与普通金属裸支架的生物相容性比较分析的基础上,对药物洗脱支架置入后的再狭窄进行了临床研究,探讨了支架再狭窄产生的原因并从临床实例角度综合研究了药物洗脱支架置入后再狭窄的新进展与启示。The most improvement of drug-eluting stent superior to bare metal stent is that drug-eluting stent contains drug vector and drug. Although the success rate of coronary stenting and security was improved, restenosis is still an obstacle to limit stent application. Allergic reaction following drug-eluting stent implantation had been reported. In this paper, based on the biocompatibility comparative analysis of general drug-eluting stent with bare metal stent, analyzed the causes, new progress and enlightenment of stent restenosis after drug-eluting stent implantation.

关 键 词：冠状动脉粥样硬化性心脏病 药物洗脱支架 裸支架 生物相容性 

分 类 号：R318[医药卫生—生物医学工程]