肺心固本冲剂治疗缓解期慢性肺原性心脏病的临床和实验研究  

CLINICAL AND EXPERIMENAL STUDY ON CHRONIC PULMONARY HEART DISEASE At REMISSION STAGE TREATED WITH FEIXINGUBEN INFUSION

作　　者：宋康[1] 徐志瑛[1] 要全保 葛琳仪[1] 蔡宛如[1] 汤军[1] 

机构地区：[1]浙江省中医院,杭州310006

出　　处：《中国中医药科技》1998年第4期199-200,共2页Chinese Journal of Traditional Medical Science and Technology

基　　金：浙江省科委自然科学基金科研项目

摘　　要：本研究旨在寻找促进肺心病患者康复,防止心肺功能减退的有效制剂,对肺心固本冲剂治疗219例缓解期肺心病患者进行疗效观察,并以66例做对照观察,并进行有关动物实验。结果表明:肺心固本冲剂治疗组显效率,有效率及总有效率分别为20.1％、60.3％、80.4％,明显优于对照组(P<0.01),治疗组T淋巴细胞活性百分率也明显增加,较治疗前有显著差异(P<0.01)。实验研究表明肺心固本冲剂对造模大鼠动脉血氧分压、右室心肌重量、肺体积、肺平均内衬间隔和单位面积肺泡个数等指标有明显改善。由此提示肺心固本冲剂是肺心病缓解期治疗的有效制剂。In order to search effective formula to promote the recovery of chronic pulmonay heart disease and pre-vente the attenuation of cardio- pulmonary function, 219patients with pulmonary heart disease at remission stage treated with feixinguben infusion were observed, 66cases were used as control group. animal experimental study was done at same time. The results showed that the curative effect of group with infusion was beter than that of control group ( p < 0.01) , ANEN of patients with infusion increased significantly, there was obvious difference between untreated and treated(p < 0.01) . Experimental study results showed that feixinguben infusion could significantly improve the modeling rat' s partial pressure of oxygen in arterial blood, myocardia weight ventricle, pulmonary volume, alveder number per unie, etc. All these suggested that feixinguben infusion was a kind of effective fomula for patients with pulmonay heart disease at remission stage.

关 键 词：肺心病 中医药疗法 肺心固本冲剂 实验 

分 类 号：R259.415[医药卫生—中西医结合]