人工泪液对干眼症患者眼像差及角膜地形图的影响  

Changes in ocular aberration and corneal surface regularity after instillation of artificial tears in dry-eye patients

作　　者：郝风芹[1] 张杰[1] 刘建亮[1] 刘育霞[1] 李艳[1] 

机构地区：[1]山东潍坊医学院眼科中心,山东省潍坊市261031

出　　处：《中国实用眼科杂志》2009年第7期763-765,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的观察干眼症患者滴用人工泪液后眼像差和角膜地形图的改变。方法对18例（30只眼）干眼症患者滴用人工泪液前、用药后即刻和用药10min后进行眼像差和角膜地形图的测量，分析指标为像差均方根值（RMSg），垂直慧差（C7），水平慧差（C8），球差（C12），角膜表面规则性指数（SRI）和角膜表面不对称指数（SAI），采用重复测量方差分析方法对数据进行分析，以P〈0．05认为差异具有统计学意义。结果用药后即刻测得的RMSg、C7、C8、C12、SRI和SAI值较用药前明显下降（P≤0．01），指标在用药10min时仍然维持稳定。结论人工泪液可以改变干眼症患者角膜表面的不规则性参数，从而通过改变RMSg、C7、C8、C12、SRI和SAI值来改善其光学视觉质量。Objective To investigate the changes ofwavefront aberration and corneal surface regularity in dry-eyes patients after instillation of artificial tears.Methods The study comprised 30 eyes of 18 volunteers in whom dry-eye had been diagnosed.The wavefront aberration measurements and corneal surface regularity measurements were done on dry eye patients before instillation of artificial tears and 1 second and 10 minutes after instillation of artificial tears .High order aberration （RMSg）, spherical aberration （ C 12 ）, horizontal coma （C8）, vertical coma （ C7 ）and corneal surface regularity （SRI） （ SAI）were collected.The results were analyzed with software of SPSS 12.0.Results The RMSg, C 12, C8, C7, SRI and SAI decrease significantly 1 second after instillation of artificial tears （P≤0.01 ）, and were stead 10 minutes later.Conclusions Instillation of artificial tears can release the irritations and improve visual quality.The wavefront aberration measurements and corneal surface regularity measurements may be useful to evaluate the benefits of artificial tears instillation in dry-eve patients.

关 键 词：干眼症 人工泪液 眼像差 角膜地形图 泪膜 

分 类 号：R16[医药卫生—公共卫生与预防医学] R779.63