耐甲氧西林的耳葡萄球菌与人葡萄球菌耐药性检测  

Meticillin-resistant Staphylococcus Isolates in Staphylococcus auricularis and Staphylococcus hominis and Their Drug Resistance

作　　者：周仲松[1] 熊自忠[1] 李睿[1] 

机构地区：[1]安徽医科大学第一附属医院感染病科,安徽合肥230022

出　　处：《中华医院感染学杂志》2009年第13期1737-1738,共2页Chinese Journal of Nosocomiology

基　　金：安徽省优秀青年科技基金(08040106815);安徽省高等学校省级自然科学研究基金(KJ2007B145)

摘　　要：目的了解临床分离的耐甲氧西林耳葡萄球菌和人葡萄球菌的发生率及其对抗菌药物的耐药性。方法采用头孢西丁纸片法检测耐甲氧西林菌株,琼脂稀释法测定耐甲氧西林菌株对多种抗菌药物的敏感性。结果耐甲氧西林耳葡萄球菌和人葡萄球菌的发生率分别为94.7%、91.7%;耐甲氧西林菌株对青霉素、四环素、环丙沙星和克林霉素、头孢唑林、头孢呋辛、头孢曲松的耐药率均>20.0%;对阿米卡星、利福平较为敏感,对万古霉素、替考拉宁的耐药率为0。结论临床分离的耐甲氧西林耳葡萄球菌和人葡萄球菌的发生率高,对多种抗菌药物耐药显著。OBJECTIVE To investigate the prevalence of meticillin-resistant Staphylococcus （MRS） isolates in Staphylococcus auricularis and S. hominis and detect their drug resistance. METHODS MRS isolates were detected by cefoxitin disc test and susceptibilities were tested by agar dilution method. RESULTS 94. 7% and 91.7% MRS isolates were in S. auricularis and S. hominis. MRS strains were resistant to most of antimicrobial agents. There were no isolates resistant to vancomycin and teicoplanin. CONCLUSIONS MRS isolates are highly prevalent in S. auricularis and S. hominis with resistance to most of antimicrobial agents.

关 键 词：耳葡萄球菌 人葡萄球菌 耐甲氧西林葡萄球菌 耐药性 

分 类 号：R378.11[医药卫生—病原生物学]