心叶淫羊藿化学成分研究  

Chemical constituents of Epimedium brevicornum

作　　者：杨云[1] 张寒娟[1] 贺海花[1] 朱振华[1] 

机构地区：[1]河南中医学院药学院,河南郑州450008

出　　处：《中草药》2009年第7期1026-1030,共5页Chinese Traditional and Herbal Drugs

基　　金：郑州市科技攻关项目(074SGY33203-3)

摘　　要：目的研究心叶淫羊藿Epimedium brevicornum的化学成分。方法通过多种色谱手段,对淫羊藿的叶子进行成分分离,通过理化方法和化合物波谱数据进行结构鉴定。结果分离得到10个化合物,分别鉴定为对硝基乙基苯酚(Ⅰ)、毛柳苷(沙立苷,Ⅱ)、5,7,4′-三羟基-8,3′-二异戊烯基黄酮(Ⅲ)、山柰酚-3-O-α-L-鼠李糖苷(Ⅳ)、宝藿苷-Ⅰ(Ⅴ)、箭藿苷B(Ⅵ)、鼠李糖基淫羊藿次苷(Ⅶ)、7,3′,4′,5′-四羟基黄酮醇(Ⅷ)、去甲基淫羊藿素(Ⅸ)、1-O-β-葡萄糖苷-1,4-二羟基-2-(3′-羟基-3′-甲基丁基)苯(Ⅹ)。结论化合物Ⅰ、Ⅱ、Ⅳ、Ⅹ为首次从本属植物中分离得到,化合物Ⅵ为首次从本植物中分离得到。Objective To study the chemical constituents of Epimedium brevicornum. Methods Com- pounds were isolated with various chromatographic techniques, their structures were elucidated by physi- cochemical methods and spectral analysis. Results Ten compounds were obtained and identified as p- nitroethylphenol （ Ⅰ）, salidroside （ Ⅱ ）, 5, 7, 4＇-trihydroxy-8, 3＇-diprenylflavone （Ⅲ ）, kaempferol-3-O- a-L-dirhamnoside （IV）, baohuoside- I （ V ）, sagittatoside B （ VI ）, 2″-O-rhamnosylicariside Ⅱ （Ⅶ ）, 7, 3＇, 4＇, 5＇-tetrahydroxyflavanol （Ⅷ）, desmethylicaritin （ IX ）, and 1-O-^-glucopyransosyl-1, 4-dihydroxy-2- （3＇-hydroxy-3＇-methylbutyl） benzene （X）. Conclusion Compounds Ⅰ , Ⅱ , Ⅳ, and X are isolated and identified from the plants of Epimedium L. for the first time and compound Ⅺ is isolated from the title plant for the first time.

关 键 词：心叶淫羊藿 对硝基乙基苯酚 沙立苷 

分 类 号：R284.1[医药卫生—中药学]