侵袭性肺部真菌感染的诊疗情况分析  

The status of diagnosis and treatment on invasive fnngal pulmonary infections

作　　者：黄金伟[1] 陈海泉[2] 余方友[3] 叶忠亮[2] 陈丽芬[1] 丁茂文[1] 李国雄[1] 

机构地区：[1]浙江省丽水市中心医院检验科,323000 [2]浙江省丽水市中心医院 感染科,323000 [3]温州医学院附属第一医院实验诊断中心

出　　处：《中华临床感染病杂志》2009年第3期151-153,共3页Chinese Journal of Clinical Infectious Diseases

摘　　要：目的调查浙江省丽水市中心医院侵袭性肺部真菌感染（IFPI）的诊断与治疗情况。方法以IFPI诊断和治疗指南为依据，分析79例诊断为IFPI患者的诊疗情况。结果确诊为IFPI且治疗有效的为6例；临床诊断病例30例，其中21例治疗后症状无明显改善，6例治疗效果明显，3例死亡；拟诊病例35例，25例临床抗真菌治疗无明显疗效，3例疗效显著，7例未进行抗真菌治疗；误诊误治8例。确诊病例病原菌以曲霉和隐球菌感染为主，抗真菌治疗时间为3～6个月。结论临床IFPI的诊断与治疗尚需进一步规范。Objective To review the status of diagnosis and treatment for invasive fungal pulmonary infections （IFPI） in Lishui Central Hospital. Methods The clinical data of 79 patients with IFPI were retrospectively analyzed. Results The diagnostic status could be classified as follows： 6 cases had confirmed diagnosis, 30 had clinical diagnosis, 35 had suspected diagnosis and 8 misdiagnosed. The treatments were all effective in 6 confirmed cases; in 30 clinically diagnosed cases, 6 were effective, 21 were ineffective and 3 died; in 35 suspected cases, 3 were effective, 25 were ineffective and 7 eases did not receive antifungal treatment. Aspergillus and Cryptococcus pulmonary infections were predominant in confirmed cases, and the antifungal treatment lasted for 3 to 6 months. Conclusion Diagnosis and treatment for IFPI need to be improved.

关 键 词：诊断 治疗 侵袭性肺部真菌感染 

分 类 号：R51[医药卫生—内科学]